Block Drug Company, Inc.

Joseph D Synodis

Alfred J Smetana

Robert C Gasman

Eddie Wong

Hal C Clarke

Kuo-Chen Yeh

James K Herms

Hyung-Kook Ahn

Stuart Wilensky

Kenneth J Markowitz

Michael C Alfano

Alan Andrew Halecky

Paul X Riccobono

Tiang Shing Chang

Richard M Lim

Frank Mazzella

Adonis Buelo

James L Gingold

Ronald S Leight

Nilofar Khaledi

Robert Charles Gasman

Hal Christopher Clarke

A denture adhesive composition is disclosed and comprises a polymeric activator in an amount of up to about 3 percent by weight based on the total weight of the denture adhesive composition; wherein the activator is selected from the group consisting of: poly(meth)acrylic acid, poly acrylic acid, polyitaconic acid, polycitraconic acid, and a monovalent alkali metal cation salt thereof. This composition exhibits enhanced adhesive performance and reduces oozing and incidence of food occlusion.

Denture adhesive compositions comprising a polymeric activator

A denture adhesive composition is disclosed and comprises a polymeric activator in an amount of up to about 3 percent by weight based on the total weight of the denture adhesive composition. This composition exhibits enhanced adhesive performance and reduces oozing and incidence of food occlusion. Also disclosed is a method of preparing a denture adhesive composition comprising: preparing a mixture which comprises a polymeric activator in an amount of up to about 3 percent by weight based on the total weight of the denture adhesive composition; forming a denture adhesive composition including the mixture; and recovering the denture adhesive composition. A method of making a denture adhesive composition more adhesive and less oozing is disclosed as well. This method comprises adding to the denture adhesive composition a polymeric activator in an amount of up to about 3 percent by weight based on the total weight of the denture adhesive composition.

Denture adhesive comprising a polymeric activator and methods of preparing the same

A denture cleansing agent containing a film forming material for preventing plaque formation. The denture cleansing agent may be a denture cleanser tablet, and the film forming material may be a polyoxyethylene oxide/vinyl acetate copolymer.

Barrier to plaque formation

The present invention comprises a concentrated solid or semi-solid disinfectant or sterilant composition for use in an aqueous disinfecting or sterilizing solution, comprising an oxidant and a protected glutaraldehyde such as a glutaraldehyde bisulfite addition compound (GBS): ##STR1## or a glutaraldehyde dioxime compound (GDO): ##STR2## The present invention further provides a method for disinfecting or sterilizing a surface or apparatus comprising the steps of mixing a concentrated solid or semi-solid glutaraldehyde sterilant composition comprising an oxidizing compound and a protected sterilant with water to form a solution and bringing the solution into contact with the surface or apparatus.

Disinfectant composition

Denture adhesive comprising a polymeric activator and methods of

Described is the use of vitamin E in topically applied compositions for the purpose of enhancing the penetration of therapeutically effective (cosmetically or pharmaceutically-active) drug or cosmetic ingredients. The topical compositions containing the penetration-enhancing concentration of vitamin E may be provided in a variety of forms including semi-solid (gel, paste, cream, lotion, ointment, etc.), liquid, suspension, film or laminate.

Penetration enhancement of topically applied therapeutic formulations

An oral composition for treatment of hypersensitive teeth in which the salty taste of the desensitizing salt, such as a potassium or strontium salt, is masked by baking soda, sodium bicarbonate.

Taste masked desensitizing compositions

A denture adhesive composition contains a denture adhesive and a pharmacologically acceptable carrier in which the denture adhesive is a salt of a copolymer of maleic acid or anhydride and a 1 to 5 carbon atom alkyl vinyl ether having a specific viscosity of at least 4.0. The denture adhesive composition is used to adhere a denture to the oral mucosa.

Denture adhesive composition

A denture adhesive with significantly improved hold performance is comprised of the mixed partial salts of polymethyl vinyl ether maleic acid. At least one of said salts comprises zirconium while a second salt is selected from the group consisting of calcium, zinc, magnesium, iron, strontium and mixtures thereof. Optionally, a tripartite salt formulation may be prepared utilizing sodium, lithium or potassium. The adhesives are formulated in a standard pharmaceutically acceptable vehicle comprised of waxes, oils, colorants, viscosity modifiers and the like as is known in the art. The denture adhesive may be formulated as a paste, powder or liquid which has rapid absorption characteristics for faster swelling softening and superior coalescence.

Denture adhesive containing partial zirconium, calcium, sodium gantrez

Phosphate-free oral compositions containing cationically charged colloids are effective to treat tooth hypersensitivity.

Relief of dentinal hypersensitivity by submicron particles

Denture cleanser tablet compositions are disclosed which include a flavoring agent in one layer and a bleaching agent in a second layer. This arrangement avoids deterioration of the tablet flavor and taste during storage.

Organoleptically stable denture cleanser tablets

An improved denture adhesive that exhibits superior tack, adhesion, cohesive strength and spreadability characteristics is made from a hydrocarbon-free base consisting of a mixture of medium length chain triglycerides which have been mixed with a small amount of fumed silica and other components so as to improve the viscosity, spreadability and taste. Preferred triglycerides include captic and caprylic acids and in particular, a mixture of the caprylic and captic acids which are combines with fumed silica and a water soluble cellosic polymer and a synthetic methyl vinyl ether/maleic anhydride copolymer that is formulated as a paste or gel.

Hydrocarbon free denture adhesive

A novel denture adhesive composition contains an adhesive mixture comprising sodium carboxymethyl cellulose and, either a partially neutralized sodium, magnesium, zinc mixed salt or a partially neutralized magnesium, zinc mixed salt of an alkyl vinyl ether maleic acid copolymer.

Denture adhesive

A composition containing a water soluble or water swellable polyelectrolyte or salts thereof in a dentifrice base or other oral compositions which can be used for relieving pain and discomfort caused by hypersensitive teeth. The salts can be single or mixed partial salts of the polyelectrolyte.

Dentinal desensitizing compositions

A toothpaste having high polishing and cleaning properties suitable for use in the removal of coffee and tea stains comprises about 10-35% of an abrasive system combined with a non-toxic paste, said abrasive system comprising a combination of anhydrous aluminum silicate and diatomaceous silica in a ratio of about 0.5:1-1.5:1, said toothpaste having a radioactive dentin abrasion index not in excess of about 150. The system provides excellent fluoride stability during storage and does not interfere with fluoride bioavailability.

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Summit, NJ, United States of America

Joseph D Synodis