Colgate Palmolive Company

Joseph Convery

Harsh Mahendra Trivedi

Long Pan

Shaotang Yuan

Zhiqiang Liu

Lisa Manus

Michael Fitzgerald

The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(CHNO)Cl]Cl, in which a zinc compound selected from ZnO and ZnCl, is reacted with a lysine compound selected from lysine and lysine.HCl, in aqueous acid. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

Low pH sysnthesis of zinc-lysine complex

Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

Two component compositions containing zinc amino acid halide complexes and cysteine

Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

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Jackson, NJ, United States of America

Joseph Convery