Pronova Solutions, LLC

Nanotek, LLC

Other

Joseph C Matteo

Jonathan Huber

Aaron Jacques

Peter Hansen

Tyler Evors

Jacob Shamblin

Stephen Andrew Latham

Niek Schreuder

Steve Schrick

Ian Turnbull

Vladimir Derenchuk

Ron Moore

Terry Douglass

Yan Zhang

A proton treatment system including a proton accelerator structured to generate a proton beam, a beamline pathway configured to direct the proton beam from the proton accelerator to at least one treatment room, a magnet assembly, including superconducting magnets, located in the beamline pathway and configured to transport the proton beam away from the accelerator into the at least one treatment room, an achromat, configured as an achromatic superconducting magnet assembly, that bends the proton beam away from the proton accelerator toward the at least one treatment room, and a collimator provided inside the achromat and configured to select the proton beam with desired energy levels.

Energy selection system for compact proton therapy

A fly-fishing reel having with a modular weight system for customizing the weight of the fly-fishing reel in order for an angler to use the fly-fishing reel with a variety of fly rods and still maintain a desired balance point and an integrated incremental meter device. The modular weight system allows the balance point of the rod and fly-fishing reel to be adjusted. The incremental metering device is adapted for keeping a tally of selected data, such as, though not limited to, the number of fish caught or released.

Fishing reel with incremental metering system and modular balancing weights

A system proton treatment system including a proton accelerator structured to generate a proton beam, a plurality of beamline pathways configured to direct the proton beam from the proton accelerator to a corresponding plurality of treatment rooms, a rotatable bending magnet located between the proton accelerator and the plurality of treatment rooms, the rotatable bending magnet being structured to selectively rotate between multiple treatment rooms, and an upright patient positioning mechanism disposed in each of the treatment rooms, the upright patient positioning mechanism being structured to support a patient within a particular treatment room and to rotate the patient between a fixed imaging source and imaging panel.

Compact proton therapy systems and methods

A fly-fishing reel having an integrated incremental meter device along with a modular weight system for customizing the weight of the fly-fishing reel in order for an angler to use the fly-fishing reel with a variety of fly rods and still maintain a desired balance point. The modular weight system allows the balance point of the rod and fly-fishing reel to be adjusted. The incremental metering device is adapted for keeping a tally of selected data, such as, though not limited to the number of fish caught or released.

Systems and methods of controlling characteristics of a proton beam emitted from a nozzle of a proton treatment system including one or more beam modifying members to define a characteristic of an emitted proton beam, and a clamping member mounted to the nozzle, the clamping member having one or more receiving portions to receive the one or more beam modifying members therein. In some embodiments, the beam modifying members comprise plate structures and the receiving portions include a plurality of slots spaced apart from one another on opposing surfaces of the clamping member to receive opposing ends of the plate structures.

Systems and methods of modifying a proton beam in a proton treatment system

Methods of projecting an image onto a patient to aid delivery of proton therapy, including capturing a first image of a patient's treatment volume, processing the image to generate a treatment volume image corresponding to at least a portion of the treatment volume, generating a scan pattern to deliver a particle beamline to at least a portion of the treatment volume, projecting the treatment volume image and the scan pattern onto the skin of the patient proximate the treatment volume, and delivering the particle beamline to at least a portion of the treatment volume to match dimensions of the treatment volume image and the scan pattern.

Methods of projecting an image to aid proton therapy

A gantry wheel adjustment system and method to adjust a gantry wheel of a proton treatment system, including an estimation unit to estimate a bearing adjustment value for each of the adjustable bearings based on a stiffness parameter of each adjustable bearing, the stiffness parameter being a function of a force applied at each adjustable bearing and a deflection of the gantry wheel associated with the force applied at each adjustable bearing, the bearing adjustment value corresponding to a nominal position value for each adjustable bearing to compensate for gantry wheel flexing when the gantry wheel is rotated from a first angular position to a second angular position, the adjustable bearings being configured to support the gantry wheel on the bearing surface and maintain the proton beam at the isocenter of the gantry wheel during gantry wheel rotation.

Systems and methods of adjusting a rotating gantry system

Treatment volume projection systems and methods for use in treating patients, including an image scanner to capture an image of a patient's treatment volume, a processor to process the image to generate a treatment volume image corresponding to at least a portion of the treatment volume, and an image projector to project the treatment volume image onto a projection surface. The treatment volume image can include an x-y scanning area of the treatment volume to assist delivery of treatment to the patient.

Proton treatment location projection system

An operator positioning apparatus for a proton treatment system includes: a proton beam nozzle to emit a proton beam to a targeted region of a patient; a gantry wheel having a front face to support the proton beam nozzle to direct the proton beam to an isocenter of the gantry wheel corresponding to a center of the targeted region, wherein the gantry wheel rotates the proton beam nozzle around the isocenter; an active floor that horizontally translates across the front face of the gantry wheel, the active floor having an opening having a width through which the proton beam nozzle protrudes when the proton beam nozzle is located below the targeted region.

Active floor for proton therapy

A gantry apparatus for a proton treatment system, including a proton beam nozzle to emit a proton beam to a targeted region of a patient, a gantry wheel to support the proton beam nozzle to direct the proton beam to an isocenter of the gantry wheel corresponding to a center of the targeted region, a plurality of adjustable bearings incrementally spaced apart along an outer diametrical surface of the gantry wheel, and a bearing surface to support a portion of the adjustable bearings such that when the wheel is rotated from a first angular position to a second angular position, at least a portion of the bearings contact the bearing surface to raise or lower the gantry wheel to realign the proton beam to the center of the targeted region.

Proton treatment gantry system

An evaporator and concentrator in a reactor and loading system concentrates ions such as fluoride ions in some embodiments, and evaporates micro- to milliliter volumes of liquid solutions including intermediate and final product in other embodiments. It efficiently re-dissolves the evaporated solution generating a product, which is transferred to an external system as desired. The external system may be a micro-fluidic reactor system and/or loading system. The evaporator/concentrator has an input port for introducing liquids and solids. A capillary tube introduces gas, such as nitrogen gas, into a volume of solution contained within a v-vial, which produces an evaporating micro bubbler. A concentric tube, surrounding the capillary tube in some embodiments, introduces gas into the empty volume above the solution inside the v-vial, which is referred to as a vapor sweep. The vapor sweep assists in removing the evaporated solution from the v-vial through a vacuum tube.

Evaporator and concentrator in reactor and loading system

A microfluidic reactor cartridge having glass capillary tubing wound in a coil and surrounded by a ceramic housing capable use in high temperatures and method for using same. In another embodiment, the microfluidic cartridge is a serpentine reactor cartridge with a serpentine microreactor channel formed in a ceramic housing. The serpentine reactor cartridge has an inlet tube attached to its inlet port and an outlet tube attached to its outlet port. The inlet port is a macro/micro interface and the outlet port is a micro/macro interface useful in gas phase reactions where solids must be used to produce a reactant. The method for using a microfluidic reactor cartridge includes two phases, the first phase for producing a radioactive labeled gas such as methyl iodide and the second phase is a methylation reaction.

Modular and reconfigurable multi-stage high temperature microreactor cartridge apparatus and system for using same

A modular and reconfigurable multi-stage microreactor cartridge apparatus provides a manifold for removably attaching multiple microfluidic components such as microreactors. The microfluidic components are attached at microfluidic component ports having two input/output terminals, which microfluidic component ports are connected via connections internal to the manifold to other microfluidic component ports providing a microfluidic circuit. The microfluidic component may be a microfluidic circuit plug-in or a cartridge having a mounting block with two input/output terminals and a fastener aperture and fluidic tubing having a first and second transport portion and a body portion, the three portions being disposed in substantially parallel planes and the body portion being would in a coil around a spool. The coil is connected to the mounting block by either epoxy protector or L-bracket. The cartridge has a first and a second remote input/output terminal connected to the first and second transport lines respectively.

Modular and reconfigurable multi-stage microreactor cartridge apparatus

A triple epicyclic differential transmission for converting three parallel inputs to three orthogonal outputs. The triple epicyclic differential transmission includes three input shaft/pinion assemblies and a ring gear assembly which includes three ring gear pairs--each pair driven by an input shaft/pinion assembly in an epicyclic manner. An outer structure assembly is rotatably mounted to the ring gear assembly and an idle pulley assembly is pivotably mounted to the outer structure assembly. An output pulley assembly is rotatably mounted to the idle pulley assembly and driven by the ring gear assembly via the idle pulley assembly.

Growing community of inventors

Walland, TN, United States of America

Joseph C Matteo