Life Technologies Corporation

Xerox Corporation

Other

Measho, Berhane

Joseph August Bartel

Joseph A Treadway

Eric Tulsky

Yongfen Chen

Enno Eric Agur

Patricia Ann Burns

Donald A Zehnder

Marc D Schrier

Maria N V McDougall

Eric Welch

Edward Graham Zwartz

Richard P N Veregin

Raj D Patel

Daryl Walter Vanbesien

Michael A Hopper

Paul Joseph Gerroir

Scott Sweeney

Timothy Jason Carter

Wenxi Huang

Chad Teters

Noah Lermer

Ke Zhou

T Brian McAneney

Shigang S Qiu

Richard P Veregin

Vladislav Skorokhod

Danielle C Boils

Emily Louise Moore

Maria N McDougall

Sheau V Kao

Kari N Haley

Danielle C Boils-Boissier

Wafa Faisul Bashir

Michael Ignatius

Elena Molokanova

Alexei Savtchenko

Berhane Measho

Weiwen Zhao

T Brian Mcaneney

Richard Pn Veregin

Maria N Mcdougall

Wafa F Bashir

Scott F Sweeney

Chad N Teters

Maria N V Mcdougall

Semiconductor nanocrystals prepared using a mixture of organic ligands (e.g., oxoacids), as well as compositions, kits, and methods of using such semiconductor nanocrystals are disclosed.

Preparation of nanocrystals with mixtures of organic ligands

A population of bright and stable nanocrystals is provided. The nanocrystals include a semiconductor core and a thick semiconductor shell and can exhibit high extinction coefficients, high quantum yields, and limited or no detectable blinking.

Nanocrystals with high extinction coefficients and methods of making and using such nanocrystals

Semiconductor nanocrystal compositions comprising magnesium containing shells and methods of preparing them are described. The compositions provide strong emission in the blue and green wavelengths as well as chemical and photostability that have not been achieved with conventional shell materials.

Magnesium-based coatings for nanocrystals

Methods for preparing core/shell nanocrystals are provided, using mismatched shell precursors and an electron transfer agent to control the nucleation and growth phases of particle formation. One method includes forming a reaction mixture comprising a plurality of nanocrystals, a first shell precursor, a second shell precursor, a weak electron transfer agent, and optionally a solvent, wherein, the first shell precursor and the second shell precursor have different oxidation states; and heating the reaction mixture to a temperature high enough to induce formation of the shell on each of the plurality of nanocrystals.

Methods for preparation of nanocrystals using a weak electron transfer agent and mismatched shell precursors

Nanocrystals having an indium-based core and methods for making them and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide higher quantum yields than known nanocrystals of similar composition, and they provide special advantages for certain applications because of their small size.

Stable indium-containing semiconductor nanocrystals

A method is provided for preparing luminescent semiconductor nanoparticles composed of a first component X, a second component A, and a third component B, wherein X, A, and B are different, by combining B with X and A in an amount such that the molar ratio B:(A+B) is in the range of approximately 0.001 to 0.20 and the molar ratio X:(A+B) is in the range of approximately 0.5:1.0 to 2:1. The characteristics of the thus-prepared nanoparticles can be substantially similar to those of nanoparticles containing only X and B while maintaining many useful properties characteristic of nanoparticles containing only X and A. The nanoparticles so prepared can additionally exhibit emergent properties such as a peak emission energy less than that characteristic of a particle composed of XA or XB alone; this method is particularly applicable to the preparation of stable, bright nanoparticles that emit in the red to infrared regions of the electromagnetic spectrum. Luminescent semiconductor nanoparticles having exemplary properties are also provided.

Preparation of stable, bright luminescent nanoparticles having compositionally engineered properties

The use of nanostructures to monitor or modulate changes in cellular membrane potentials is disclosed.

Activation and monitoring of cellular transmembrane potentials

A method for isolating a nanoparticle is disclosed. A medium containing a nanoparticle is provided. The medium is acidified with a weak acid. An alcoholic solvent is added to induce the nanoparticle to precipitate from the medium. The precipitated nanoparticles are separated from the medium.

Methods for isolating and purifying nanoparticles from a complex medium

Nanocrystals having a ZnTe core and methods for making and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide quantum yields and stability suitable for applications such as flow cytometry, cellular imaging, and protein blotting, medical imaging, and other applications where cadmium toxicity is an issue.

Methods for preparation of ZnTe nanocrystals

A method is provided for preparing luminescent semiconductor nanoparticles composed of a first component X, a second component A, and a third component B, wherein X, A, and B are different, by combining B with X and A in an amount such that the molar ratio B:(A+B) is in the range of approximately 0.001 to 0.20 and the molar ratio X:(A+B) is in the range of approximately 0.5:1.0 to 2:1. The characteristics of these nanoparticles can be substantially similar to those of nanoparticles containing only X and B while maintaining many useful properties characteristic of nanoparticles containing only X and A; and can additionally exhibit emergent properties such as a peak emission energy less than that characteristic of a particle composed of XA or XB alone. This method is particularly applicable to the preparation of stable, bright nanoparticles that emit in the red to infrared regions of the electromagnetic spectrum.

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Dublin, CA, United States of America

Joseph August Bartel