Schering Corporation

Other

Joseph A Marquez

Marvin J Weinstein

Gerald H Wagman

Mahesh G Patel

Ann C Horan

Raymond T Testa

Peter J Daniels

J Allan Waitz

David Taplin

Bong K Lee

Dinanath F Rane

Jay A Waitz

George H Miller

Min Chu

Vinod R Hegde

Raymond Cooper

Manohar G Kalyanpur

Richard W Vaughan

Paul D Watkins

A handheld cup counter is disclosed. The cup counter may have a mechanical or optical sensor used to count the number of brim portions within a stack of cups. In order to properly position the optical or mechanical sensor, the sensor is disposed in relation to a ridge plate that helps the user to properly align the sensor to the stack of cups so that the sensor may accurately sense the number of brim portions within the stack of cups. The cup sensor may also have additional calculator functionality that works in conjunction with the sensed number of cups in order to more efficiently add and subtract the sensed number of cups of a plurality of stack of cups.

Cup counter

Two novel glycosides of 3'-deoxyaquayamycin isolated from an antimicrobial complex produced in fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces sp. SCC 2136, ATCC 55186 are disclosed.

Glycosides of 3'-deoxyaquayamycin antibiotics

Novel macrocyclic lactone antibacterials isolated from a culture containing the microorganism S. aerocolongenes sub sp. antibiotica SCC 1886, ATTC 55003 and their use for treating and/or preventing antibacterial infections, especially Chlamydia infections are disclosed.

Macrocyclic lactone antibacterial antibiotic compounds

The novel triacetylenic dioxolone antifungal compound of this invention is isolated from the EV-22 complex of this invention which is elaborated by the microorganism Microbispora sp. SCC 1438, ATCC 53620.

ATCC 53620 production of a triacetylenic dioxolone with Microbispora sp.

A compound represented by the formula I: ##STR1## wherein R.sub.1 and R.sub.2 are independently hydrogen or (C.sub.2 -C.sub.10) alkanoyl in substantially chemically pure form, and pharmaceutical compositions thereof are disclosed.

Polycyclic aromatic antifungal compounds

Antifungal triacetylenic dioxolone from Microbispora sp. SCC 1438, ATCC

The antibiotic 7273 complex is elaborated by the microorganism, Dactylosporangium vescum ATCC 39499. The novel 7-chloro-4a-hydroxy-8-methoxytetracycline isolated from antibiotic 7273 complex is active against gram-positive and gram-negative aerobes.

7-chloro-4a-hydroxy-8-methoxytetracycline, antibiotic compositions

The antibiotic 13-384 complex is elaborated by a new variety of Micromonospora carbonacea; namely Micromonospora carbonacea var africana NRRL 15099.

Antibiotic 13-384 complex from Micromonospora carbonacea var africana

The novel antibiotic complex designated hazymicin consisting of eight components, is produced by a novel strain of Micromonospora herein designated Micromonospora echinospora var. challisensis SCC 1411. Also disclosed are the structures of the two components namely, Component 5 and Component 6.

Broad spectrum antibiotic complex produced by a novel micromonospora

A microorganism of the genus Acetinoplanes produces a novel complex of polyene antibiotics herein designated collectively Antibiotic 67-121 (and sometimes referred to as the Antibiotic 67-121 complex). The individual components are designated Antibiotic 67-121A, Antibiotic 67-121B, Antibiotic 67-121C and Antibiotic 67-121D. The individual components have ultraviolet spectra characteristic of heptaenes. Further, they are orally active against a variety of strains of Candida albicans including many clinical isolates thereof.

Antibiotic 67-121, a new polyene antifungal antibiotic produced by

The AR-5-3 Complex consisting of four macrolide antibiotics is elaborated by a mutant strain of Micromonospora polytrota. The antibiotics exhibit substantial activity against gram positive bacteria in vitro and in vivo.

Macrolide antibiotic complex

The microorganisms Micromonospora inyoensis 1550F-1G and M. purpurea strain 1124 each microbiologically convert tobramycin, kanamycin A, kanamycin B and dibekacin to their respective 3'-N-methyl and 3'-N-methyl-4'-C-methyl derivatives. The derivatives exhibit significant activity against representative gram positive and gram negative bacteria and may also be converted to other derivatives which have significant antibacterial activity.

Microbiological methylation of aminoglycosyl-aminoglycosides

Rosaramicin, (also known as rosaramicin) a new broad spectrum antibiotic is described together with methods for its production via the cultivation under controlled conditions of Micromonospora rosaria, a new species of Micromonospora, and to methods for purifying and using the same. Its 2'-monoesters and its 3,2'-diesters and their acid addition salts also possess antibiotic activity.

Method for producing rosaramicin (rosamicin)

A novel antibiotic complex exhibiting antifungal activity is produced by fermenting a novel species of bacteria from the genus Aeromonas, the bacterium being herein designated Aeromonas sp. W-10. The antibiotic complex is comprised of at least three and possibly as many as six components and has been designated Antibiotic W-10 Complex. Two members of the complex have been isolated in substantially pure form and are designated Antibiotic 20561 and Antibiotic 20562, the antibiotics exhibiting substantial antifungal activity.

Growing community of inventors

Montclair, NJ, United States of America

Joseph A Marquez