Schering-plough Healthcare Products Inc.

Schering Corporation

Joseph A Haslwanter

William F Rencher

Thomas J Laughlin

Gerald R Dever

Kurt G Van Scoik

David M Oakley

William J McLaughlin

An aqueous-based sprayable composition comprises a therapeutic or palliative agent, water and a mixture of microcrystalline cellulose and alkali metal carboxyalkylcellulose. In one embodiment, the composition is a non-Newtonian nasal spray exhibiting a very rapid viscosity recovery upon removal of shear forces.

Spray composition

Aqueous nasal spray compositions comprising a medicament and an aqueous carrier comprising water soluble polymers selected from the group consisting of polyvinylpyrrolidone and mixtures thereof.

Nasal spray compositions

A skin barrier lotion for protection against contact with irritants comprises: about 5 to 15 percent by weight of a long-chain fatty acid; about 1 to 5 percent by weight of a long-chain fatty alcohol; about 1 to 10 percent by weight of a hydrocarbon oil; about 1 to 30 percent by weight of a silicone skin protectant; about 0.5 to about 5 percent by weight of an alkanolamine; about 0.5 to about 5 percent by weight of a humectant; about 0.5 to about 10 percent by weight of an inorganic skin protectant; about 0.5 to 15 weight percent of a preservative; and about 50 to 90 percent by weight water. Optionally, the lotion will also contain up to about 5 percent by weight of a fragrance, odor neutralizer or a mixture thereof.

Skin barrier composition

Spray composition with reduced dripping

Oxymetazoline HCI and/or chlorpheniramine maleate nasal spray compositions

Stable sulfide-containing compositions have been developed. The stable sulfide-containing composition comprises a) a sulfide, a polysulfide or mixtures thereof, of an alkali or an alkaline earth metal, and b) a carrier, such that after maintaining the sulfide-containing composition at a temperature of about 37.degree. to about 50.degree. Celsius for about 2 weeks to one month, the sulfide content remaining in the sulfide-containing composition is about 90% or greater of the initial sulfide content. The sulfide-containing compositions can be used for relieving the pain of ingrown toenail by softening the nail, or as a depilatory for removing human hair or hair from animal hides.

Stable sulfide compositions, uses, and process for preparation thereof

Aqueous nasal spray compositions containing:

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Germantown, TN, United States of America

Joseph A Haslwanter