Boston Scientific Scimed, Inc.

Epix Therapeutics, Inc.

Ep Technologies, Inc.

Scimed Life Systems, Inc.

Boston Scientific Corporation

Advanced Cardiac Therapeutics, Inc.

Verix Health, Inc.

Koninklijke Philips Corporation N.v.

Pfix, Inc.

Other

Meridian Medical Systems, LLC

Boston Scientifc Corporation

Josef Vincent Koblish

David K Swanson

Dorin Panescu

Russell B Thompson

Jessi E Johnson

Eric Andrew Schultheis

Isaac J Kim

James G Whayne

Thomas R Jenkins

Donghoon Chun

Sidney D Fleischman

Boaz Avitall

Raj Subramaniam

Zaya Tun

Yi Yang

Huy D Phan

Edward J Snyder

Minhchau N Cao

Eza Koch

Chau Cao

Frank W Ingle

Robert F Bencini

George J Klein

Thomas P Coen

David L McGee

Szabolcs Deladi

Kurt D Sparks

Simplicio Velilla

Darrell L Rankin

Mark D Mirigian

Guy R Harvey

Roger Noel Hastings

Benjamin E Morris

Michael J Pikus

Anant V Hegde

Miriam H Taimisto

Leonard B Richardson

Tat-Jin Teo

Kevin D Edmunds

John F McCarthy

Craig R Kline

Paul A Roche

Steven E Levin

Thomas F Mirarchi

Thomas H Peterson

Leslie Oley

Jonathan A Wohlgemuth

Thomas T Coen

Kulbir S Hunjan

Kulbir Singh Hunjan

David G Lawrence

Robert Chris Allison

James Mazzone

Byron Chun

Rebecca Tin

Mark Forrest

Steve Ha

Anat V Hegde

Kenneth Michael Berliner

Riley Ennis

David Mcgee

Systems and methods for facilitating assessment and convenient display of graphical output indicative of lesion formation and outputting data indicative of lesion formation to a 3D mapping system to display on a 3D model are disclosed herein.

Lesion formation assessment and display

A pulmonary access device comprises an elongated shaft having a proximal shaft section, a bendable shaft section, a distal shaft section, and a distal tip. The pulmonary access device further comprises an elongated sheath having a proximal sheath section, a malleable distal sheath section, and working channel. The working channel is configured for slidably receiving the elongated shaft. The pulmonary access device further comprises a handle assembly including a handle body. The handle body is affixed to a proximal end of the elongated shaft. The handle body is removably affixed to a proximal end of the elongated sheath.

Lung access device

Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.

Methods of determining catheter orientation

A method comprises introducing an ablation catheter assembly into a heart chamber of the patient, deploying an ablative loop structure from an elongated shaft of the ablation catheter assembly, placing the ablative loop structure in an expanded geometry, disposing the expanded ablative loop structure on the endocardial tissue around an ostium of a blood vessel extending from the heart chamber, activating the ablative loop structure, thereby creating a circumferential lesion around the ostium of the blood vessel, disposing the ablative shaft distal end, when the ablative loop structure is housed within the elongated shaft, at a target region of the endocardial tissue remote from the ostium of the blood vessel, and activating the ablative shaft distal end, thereby creating another lesion at the target region.

Multi-use endocardial ablation catheter

A pulmonary access device comprises an elongated shaft having a proximal shaft section, a bendable shaft section, a distal shaft section, and a channel. The pulmonary access device further comprises a profiled stylet configured for being disposed in the working channel of the elongated shaft, the profiled stylet having a proximal stylet section with a first lateral stiffness profile, an intermediate stylet section having a second lateral stiffness profile less than the first lateral stiffness profile, a distal stylet section, wherein, when the profiled stylet is disposed in the working channel of the elongated shaft, the intermediate stylet section axially aligns with the bendable shaft section. The pulmonary access device further comprises a pull wire affixed to the distal shaft section, such that, when the pull wire is tensioned, the bendable shaft section bends, thereby deflecting the distal shaft section relative to the proximal shaft section.

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Methods of removing heat from an electrode using thermal shunting

Electrode assembly with thermal shunt member

Systems and methods for facilitating assessment of a nature of contact between an electrode assembly of an ablation catheter and viable body tissue are disclosed herein. In some embodiments, a method comprises obtaining a first detected voltage between a first electrode and a second electrode, wherein the first and second electrodes are positioned along an electrode assembly of the ablation catheter, and wherein the first electrode is distal to the second electrode, obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned proximal to the second electrode.

Contact assessment between an ablation catheter and tissue

Systems for determining catheter orientation

Radiometric systems may comprise a radiometer, an antenna and a processor communicatively coupled together. The processor may provide a contact-focused output based on filtering or other processing of a raw radiometric output signal. The contact-focused output may facilitate determination of whether contact has been achieved and/or assessment of contact. A miniaturized reflectometer may be configured to determine an amount of reflected power from the antenna. The processor may be configured to determine a reflection coefficient of the reflected power determined by the reflectometer and to identify tissue type based on the reflection coefficient. Systems and methods for facilitating deeper temperature measurements of a radiometer are described.

Radiometric tissue contact and tissue type detection

A steerable biopsy device comprises an outer sheath comprising a sheath body having a proximal sheath section and a distal sheath section. The outer sheath further comprises a distal sheath tip and a sheath lumen terminating at a distal port in the distal sheath tip. The biopsy device further comprises a biopsy needle integrated with the sheath body. The biopsy needle is slidably disposed in the sheath lumen. The biopsy needle comprises a needle shaft and a distal needle tip configured for being displaced between a stored position within the sheath lumen and a deployed position outside of the distal port of the distal sheath tip. The biopsy device further comprises an articulation control actuator configured for articulating the distal sheath section, and a needle actuator configured for distally advancing the distal needle tip from the stored position to the deployed position.

An ablation catheter assembly comprises an outer ablation catheter comprising an elongated shaft having a proximal shaft section and a distal shaft section, an inner lumen extending through the proximal shaft section and the distal shaft section, a distal tip port in communication with the inner lumen, and at least one ablative element disposed on the distal shaft section. The ablation catheter assembly further comprises an inner ablation catheter slidably disposed within the inner lumen of the outer ablation catheter. The inner ablation catheter comprises an elongated inner member having a proximal member section and a distal member section, and ablative elements disposed along the distal member section. The distal member section is configured for being deployed from the distal tip port when the inner ablation catheter is distally slid within the inner lumen of the outer ablation catheter, thereby placing the distal member section into an expanded loop geometry.

Growing community of inventors

Santa Clara, CA, United States of America

Josef Vincent Koblish