Hoechst Aktiengesellschaft

Josef Musil

Wilhelm Bartmann

Ernold Granzer

Hermann Teufel

Gerhard Beck

Ulrich Gebert

Klaus Kuhlein

Adolf Heinz Linkies

Rolf-Ortwin Weber

Dieter-Bernd Reuschling

Hans-Jochen Lang

Roman Muschaweck

Rudolf Kunstmann

A physiologically-acceptable compound of one of the formulae ##STR1## wherein R.sup.1 is a member selected from the group consisting of (a) a 6-membered heteroaromatic ring with up to two ring hetero atoms selected from the group consisting of O, N and S, at most one of which is different from nitrogen, and (b) an alkyl group containing from 1 to 4 carbon atoms and substituted by such a heteroaromatic ring;

Novel derivatives of imidazole and pharmaceutical compositions

Heterocyclic sulfamoyl-aryl-ketones wherein the heterocyclic component consists of a benzofuran, indole or benzothiophene radical and the sulfamoyl-aryl moiety is ortho-substituted by halogen, methyl or trifluoromethyl having uricosuric, hypouricemic and salidiuretic action and a process for their manufacture.

Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes,

A compound of one of formulae (I) and (II) (of formula sheet) wherein

Novel derivatives of imidazole, and pharmaceutical compositions

The present application relates to novel pyrrolidones which are analogous to prostaglandins as well as to a process of preparing the same. The new compounds have valuable pharmaceutical properties and can therefore be used as medicaments.

Pyrrolidones, pharmaceutical compositions therewith and processes of use

The present invention relates to novel pyrrolidone derivatives as well as to a process of preparing the same. The novel compounds have a pharmaceutical action similar to that of prostaglandins and can therefore be used as medicaments.

Pyrrolidones and process for their manufacture

The invention relates to derivatives of 1,2-diarylethylene and to a process for their preparation. The compounds have valuable pharmaceutical properties and may be used as medicaments.

Derivatives of the 1,2-diarylethylene and pharmaceutical compositions

A medicament consisting of or containing an O-acyl-2,3-diaryl-3-halogeno-acrylaldoxime of the formula I ##STR1## in which X represents a chlorine or bromine atom, R stands for an alkyl, alkenyl, alkoxy, alkenoxy or alkylamino group having from 1 to 12 carbon atoms each, or for an aryl, aryloxy, arylalkyl, arylalkoxy, arylamino or arylalkylamino group substituted optionally by 1 or 2 alkyl groups each having from 1 to 6 carbon atoms, and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are identical or different, each representing a hydrogen atom, a halogen atom or an alkyl or alkoxy group having each from 1 to 6 carbon atoms, a process for preparing them and a method for the treatment of disorders of the purine metabolism.

Growing community of inventors

Konigstein, Taunus, Germany

Josef Musil