Rohm Gmbh Chemische Fabrik

Rohm Pharma Gmbh

Josef Mueller

Hans-Ulrich Petereit

Wolfgang Roelz

The invention relates to pharmaceutical materials for local and non-irritating therapy for psoriasis, containing antipsoriatic ingredients. The pharmaceutical material is a liquid preparation of film-forming polymers and antipsoriatic ingredients, with which the psoriasis affected skin area can be covered and treated in situ with a medicated film or foil formed at the treatment site. Dithranol and/or glucocorticoid in combination with keratolytically acting urea are preferred for use as antipsoriatic ingredients.

Pharmaceutical material for the treatment of psoriasis

A pharmaceutical preparation for topical treatment of skin disorders, particularly psoriasis, comprising active ingredients consisting essentially of combinations of 1,8,9-anthracenetriol, and/or derivatives thereof, and urea. The subject preparation is applied in an essentially water-free excipient. The preparation includes surfactants, which are ordinarily incompatible with the active ingredients. By the use of surfactant-urea combinations, surfactants can be incorporated into a stable, lipophilic pharmaceutical preparation, whereby after use the surfactants are liberated by the action of water, to form a readily washable emulsion system. The inventive preparation is advantageously used in the 'short time' method of therapy of psoriasis.

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Lindenfels, Germany

Josef Mueller