Litana Ltd.

Medinol Ltd.

A Bromberg & Co. Ltd.

Josef Flomenblit

Nathaly Budigina

Jacob Richter

Yuval Bromberg

A medical device such as a stent, surgical staple, bone anchoring device or bone fixation device, intended to be deployed within the body, composes a shape memory alloy (SMA) portion with an austenitic and unaustenitic state with different memorized configurations in each of these states. The SMA which is initially in an initial configuration in which it can be placed into position within the body, can be mechanically deformed into an operational configuration in which it remains deployed within the body.

High strength medical devices of shape memory alloy

A process is provided for the manufacture of a two-way shape memory alloy and device. The process of the invention allows a reversible adjustment of the characteristic transformation temperatures, as well as the direction of the two-way shape memory effect, at the final stage of manufacture.

Manufacture of two-way shape memory devices

A medical device which comprises a shape memory alloy (SMA) portion which is deformable from an undeformed first configuration assumed by it in an austenitic state of the SMA to a deformed second configuration, whereby the SMA is converted into a strain-induced martensite or partial martensite. This conversion increases the temperature of transformation (A.sub.s) from an initial transformation temperature A.sub.s .degree. to a temperature A.sub.s '. When the SMA, once in the second configuration, is heated to a temperature higher than A.sub.s ', it transforms to an at least partial austenite and it transforms towards the undeformed first configuration with a decrease of A.sub.s from A.sub.s ' to A.sub.s .degree.. A.sub.s .degree. is below body temperature such that when the device is deployed in the body, after placing it in its target location with the SMA portion in the second configuration and then heating it to assume its first configuration, the SMA is stable in the at least partial austenite at body temperature.

Implantable medical devices of shape memory alloy

A stent adapted for placing in the urethra so as to retain the urethra's diameter above a critical level is provided. The stent comprises:

Urological stent and deployment device therefor

A stent for placing in a tubular organ so as to support its diameter to remain above a critical diameter. The stent comprises a spiral coil or cylinder made of a two-way shape memory alloy and has a super-elastic state in which the stent's diameter is at least about the critical diameter or more but within a physiological range tolerated by the organ and having a soft state in which the stent's diameter, after changing to this state from the super-elastic state, which is less than the critical diameter. The shape memory alloy has two transition temperatures being within a range that will not damage biological tissue, of which a first transition temperature is a temperature in which it changes from the soft state to the super-elastic state and of which a second transition temperature is a temperature in which it changes from the super-elastic state to the soft state. The arrangement being such that after changing into one of the two states, the stent remains in that state at body temperature.

Growing community of inventors

Holon, Israel

Josef Flomenblit