Syntex (u.s.a.) Inc.

Molecular Devices Corporation

Other

Josef E Kercso

John Wallace Parce

Harden M McConnell

John C Owicki

Gillian M Humphries

Karen M Kercso

John McLean Morris

John P Bennett

Methods and apparatus are disclosed for detecting the effects of cell affecting agents on living cells. The method steps include providing living cells that are retained in a micro flow chamber. The micro flow chamber is adapted for either continuous or intermittent flow of solutions or suspensions in intimate contact with the cells. The solutions or suspensions, which contain a cell affecting agent, are then flowed in intimate contact with the cells and the pit is measured.

Methods and apparatus for detecting the effect of cell affecting agents

Methods are disclosed for detecting the effects of cell affecting agents on living cells. The method steps include providing living cells that are retained in a micro flow chamber. The micro flow chamber is adapted for either continuous or intermittent flow of solutions or suspensions in intimate contact with the cells. The solutions or suspensions, which contain a cell affecting agent, are then flowed in intimate contact with the cells and at least one effect of the cell affecting agent on the cells is measured by an appropriate detecting means, which is operatively associated with the micro flow chamber.

Methods for detecting the effect of cell affecting agents on living cells

Apparatus for subcutaneously implanting drug-containing pellets in animals. The apparatus comprises a handle; attached to the handle, a track along which a carriage moves; a carriage which moves along the track, the carriage having (i) a front part adapted to receive and retain a detachable needle having a passageway extending the length of the needle and (ii) a passageway extending the length of the carriage and corresponding to the needle passageway when retained in the carriage; a means to propel the carriage from the front to the rear of the track; means at the front and rear of the track to stop the carriage; a straight, retractable rod detachably attached to the rear stopping means so that the rod extends straight through the carriage passageway; a finger actuatable trigger attached to the handle to actuate the retraction of the carriage. A unique, flanged needle having a sharp metal end, an enlarged, flanged end, a passageway extending the length of the needle, and at least one pellet in the needle passageway is also described.

Implant apparatus

An intrauterine device providing a membrane to cover substantially the entire surface of the uterine cavity, said device having a Y- or V-shaped resilient member with two diverging arms, a membrane covering the entire area between the diverging arms and, in addition, extending above an imaginary line passing through the terminal ends of the arms, and a flexible tail or string connected to the intersection of the arms for aiding in the removal of the device from the uterus when desired. The ends of the diverging arms have enlarged end portions and the arms are of unequal length so that the arms may be resiliently collapsed and placed in a tubular inserter with the enlarged end portions longitudinally spaced in the inserter.

Intrauterine device

Means for supporting an object, or a portion thereof, during radiographic analysis comprising a hollow reservoir adapted to receive and hold a constant volume of fluid material within the interior thereof, said reservoir having a pouch-like flexible member forming all or a portion of one wall thereof, said pouch-like flexible member being adapted to receive and support the object undergoing analysis during radiographic exposure thereof, a second flexible member forming all or a portion of a second wall thereof, and means operatively connected to said second flexible member for moving said second flexible member so as to cause a corresponding movement of said pouch-like flexible member. During use, the second flexible member is moved in such a manner as to cause an enlargement of the pouch-like deformation of the pouch-like flexible member. After the object to be examined is inserted in the enlarged deformation, the second flexible member is moved so as to cause the pouch-like flexible member to conform to the exterior surface of the object and thereby provide proper support therefor during the radiographic procedure.

Growing community of inventors

Palo Alto, CA, United States of America

Josef E Kercso