Institute for Cancer Research

Applied Research Systems Ars Holding N.v.

Fox Chase Cancer Center

Jose Russo

Irma H Russo

Mark D Andrake

Jaak Janssens

Yanrong Su

Giampiero Deluca

Julia Santucci Pereira Del Buono

The present disclosure provides hCG variant proteins, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of treating cancer.

Human chorionic gonadotropin variant peptides and treatment of breast cancer

This relates to the prevention of cancer initiation. More specifically, the invention provides compositions and methods useful for altering the genetic signature in breast tissue, said alteration being correlated with a reduced risk for the development of breast cancer.

Compositions and methods for the prevention of cancer in high risk patients

This invention relates to the field of cancer therapy. More particularly, the invention relates to the treatment of mammary tumor, clinically manifest mammary tumor (breast cancer) and metastatic mammary tumor by administration of human Chorionic Gonadotropin (hCG). The treatment preferably comprises the administration of hCG in conjunction with an antiestrogen and/or a Type I Interferon.

hCG therapy for the treatment of breast cancer

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Rydal, PA, United States of America

Jose Russo