United Services Automobile Association (Usaa)

Genzyme Corporation

Ilex Products, Inc.

Jose Puente

James Joseph Forrester

Prasad Lakshmipathy

Jason Patrick Picarazzi

Philip Hansen

Armondo Elias Ortega

William E Bauta

William R Cantrell, Jr

Dennis P Lovett

Brian D Burke

Brian E Schulmeier

Embodiments disclosed herein describe systems and methods to generate statuses of higher level integrated logical clusters from one or more output files generated by the clusterwares of a plurality of lower level physical clusters. The systems and methods provide an interactive dashboard graphical user interface (GUI) rendering the statuses of the higher level logical clusters. In response to a drill down selection by the system administrator, the systems and methods may render resource level statuses of the plurality of resources forming the higher level logical cluster. Therefore, by using a single dashboard, a system administrator can seamlessly transition between statuses at different level of abstractions for multiple resources distributed across multiple geographically diverse datacenters. Furthermore, the dashboard allows the system administrator to perform failover operations.

Systems and methods for centralized database cluster management

The present invention for the stereoselective preparation of 2-deoxy-&#x3b2;-D-adenine nucleosides wherein a blocked 2-deoxy-&#x3b1;-D-arabinofuranosyl halide is coupled with the salt of an adenine derivative.

Process for preparing purine nucleosides

The present invention provides for the preparation &bgr;-adenine nucleosides by coupling an adenine derivative containing an unprotected exocyclic amino group at the C-6 position and a blocked arabinofuranosyl derivative, in the presence of a base and solvent. The present invention also provides for the stereoselective preparation of 2-deoxy-&bgr;-D-adenine nucleosides wherein a blocked 2-deoxy-&agr;-D-arabinofuranosyl halide is coupled with the salt of an adenine derivative. The forgoing aspects of the present invention are utilized in the preparation of a clofarabine composition wherein the ratio of &bgr; to &agr;-anomer is at least 99:1.

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San Antonio, TX, United States of America

Jose Puente