Eastman-kodak Company

Infotonics Technology Center, Inc.

Sensivida Medical Technologies, Inc.

Vuzix Corporation

Jose M Mir

John A Agostinelli

Elena A Fedorovskaya

David Lynn Patton

John Randall Fredlund

Jerry R Varner

Cecelia M Horwitz

Dilip K Chatterjee

Gustavo R Paz-Pujalt

Girish V Prabhu

Kenneth Alan Parulski

Liang-sun Hung

Serguei Endrikhovski

Tomasz A Matraszek

Clark N Kurtz

Liang-Sun Hung

Steven A Ferranti

Syamal K Ghosh

Debasis Majumdar

Dennis R Zander

John P Spoonhower

Richard N Blazey

Gopalan Rajeswaran

Peter A Parks

Paige Miller

Edward Carnall, Jr

David L Peterson

Laurie A Strom

Brian J Higberg

Gilbert Allan Hawkins

Lee William Tutt

Yee S Ng

James Michael Chwalek

Marek W Kowarz

Mark Lelental

Samuel Chen

Robert J Schultz

Mool Chand Gupta

Joseph F Revelli, Jr

William J Grande

Edward Covannon

Rajiv Mehrotra

Stacy M Munechika

Daniel D Stancil

Philip R Ashe

Myron W Culver

Arun K Mehrotra

Robert B Bilhorn

Alex A Wernberg

Tuviah E Schlesinger

Swatee N Surve

Gerrit Lubberts

Laurie Schaefer

Kamal K Sarbadhikari

John Squilla

Lauri A Strom

Ralph A Nicholas, Iii

Edward Carnall,Jr

An allergen-loadable microneedle cartridge is disclosed. The cartridge includes at least one substrate, a plurality of microneedles in a microneedle layout protruding from at least one substrate, and fillable allergen sites corresponding to the microneedle layout. The fillable allergen sites and microneedle layout are configured such that the microneedles can penetrate subject skin and deliver pharmacologically active doses of allergens in a minimally invasive process. A planar allergen filling system for loading the allergen-loadable microneedle cartridges is also disclosed. The system has a loading section with spaced-apart allergen loading sites that correspond to the microneedle layout of the microneedle cartridge. Filling wells having allergen deposition areas larger than the allergen loading sites transfer deposited allergen to the allergen loading sites through capillary channels. The allergen-loadable microneedle cartridge is loaded by contacting its fillable allergen sites with the loading section of the planar allergen filling device.

Practice-loadable minimally invasive allergy test system

A head-mounted imaging apparatus has a projector that is energizable to project image-bearing light and a light-conditioning element that directs and shapes the image-bearing light from the projector to form a real image plane. A lenslet array is positioned adjacent to the real image plane and optically disposed at substantially one focal length away from a curved mirror, wherein the surface of the curved mirror is substantially spherical. There is a beamsplitter in the path of light from the real image at the lenslet array and disposed to direct at least a portion of the light from the real image toward the curved mirror. The curved mirror directs light from the beamsplitter to form a virtual image for an observer who wears the head-mounted imaging apparatus.

Head mounted imaging apparatus with curved lenslet array

An apparatus and method for making an apparatus for skin testing includes a housing with an opening which defines a field of view of a skin testing region, an image sensing apparatus, an illumination apparatus, a binding apparatus, and an image processing controller. The image sensing apparatus is positioned with respect to the housing to capture images in the field of view provided by the opening. The illumination apparatus is positioned within the housing to direct light towards a portion of the field of view provided by the opening. The binding apparatus detachably secures the housing over the skin testing region and maintains a fixed distance between the image sensing apparatus and the skin testing region. The controller is configured to analyze test samples sites in each of the captured images from the image sensing apparatus and provide a skin test result for each of the test sample sites.

Skin test image analysis apparatuses and methods thereof

A method of determining a prothrombin time is disclosed. A mediator is applied to a stratum corneum. The stratum corneum is penetrated to allow the mediator to enter a region containing interstitial fluid and interact with at least one capillary, causing blood and/or blood components to leak from the at least one capillary into the region containing interstitial fluid. A characteristic affected by the blood and/or blood components is measured in the region containing interstitial fluid which correlates to the prothrombin time. A system for measuring prothrombin time is also disclosed. The system has a mediator, one or more microneedles, and a processor directly or indirectly coupled to the one or more microneedles and configured to determine a coagulation change in blood or blood components in a region around the one or more microneedles after the one or more microneedles penetrate a stratum corneum.

MEMS interstitial prothrombin time test

A blood monitoring system is capable of monitoring the blood of a subject in vivo. The blood monitoring system comprises: 1) an array of movable microneedle micromachined within associated wells; 2) array of motion actuators able to move each needle in and out of their associated wells; 3) array of microvalves associated with each microneedle able to control the flow of air around the microneedle; 4) an array of chemical sensors inserted into patient by movable microneedles; 5) an array of inductors able to measure chemical concentration in the vicinity of inserted chemical sensors; 6) conducting vias that provide timed actuating signal signals from a control system to each motion actuator; 7) conducting vias that transmit signal produced by array of chemical sensors to the control system for processing, although the blood monitoring system can comprise other numbers and types of elements in other configurations.

Blood monitoring systems and methods thereof

An allergy testing system includes encapsulated allergens, a microneedle array, and an activation system coupled to the microneedle array and the encapsulated allergens such that the encapsulated allergens are moved into contact with a subject as the microneedle array is moved from a resting position to a penetrating position. A method for determining a degree of reaction to one or more allergens by a patient in a minimally invasive manner is also disclosed. Penetration of one or more microneedles into a skin of the patient is caused. Each of the penetrations into the skin is exposed with an allergen from each of the one or more microneedles. One or more images are captured of each of the penetrations into the skin. Each of the captured images are analyzed to assess the degree of reaction to the specific allergen. Allergic reactivity data is output for at least one of the allergens.

Minimally invasive allergy testing system

Image-based products are obtained from a digital motion picture source by utilizing a content playing and display system for (a) displaying a sequence of motion picture image frames from a digital motion picture image source containing motion picture contents, and (b) selecting one or more of the image frames for an image-based product and obtaining a unique frame identification for said one or more selected frames; a content management system that (a) utilizes the unique frame identification and determines whether at least one permissible image-based product can be made from said one or more selected frames, and (b), if a permissible image-based product may be made as determined, obtains file data corresponding to said one or more selected frames from a digital source file containing source information corresponding to the motion picture contents; an order management system for preparing order information for the permissible image-based product from the file data; and an order fulfillment system for generating the image-based product from the file data according to the order information.

System and method for obtaining image-based products from a digital motion picture source

A method for collecting and associating affective information for at least one image in an imaging system includes displaying a digital image for viewing by a particular user; automatically collecting affective information for the digital image as the particular user views the image; and associating the affective information with the particular user.

Method for providing affective information in an imaging system

A method for determining affective information for at least one image in an imaging system includes sequentially displaying a plurality of digital images for viewing by a user; monitoring the viewing time for each of the plurality of digital images; and using the viewing time to determine affective information for at least one of the digital images.

Method for using viewing time to determine affective information in an imaging system

A method for determining affective information for at least one image in an imaging system includes displaying a digital image for viewing by a user; monitoring the facial expression of the user as the user views the digital image; and using the facial expression of the user to determine affective information for the digital image.

Method for using facial expression to determine affective information in an imaging system

A method for classifying images according to features that are relevant to potential therapeutic effect, comprising: providing an image; and classifying said image according to one or more of the following classes, landscapes, people-activity, people-expression, people-type, animals, color (dominant hue(s)), direction of light, type of light, distance, travel/offset(direction of motion/travel).

Management of physiological and psychological state of an individual using images therapeutic imaging classification system

Autostereoscopic images are produced by projecting a stereo pair of images onto a modified cube-corner retroreflective material. The cube-corner differs from that commonly available in that it has been altered to return the light to viewers eyes rather than directly back to the source of the projection.

Auto-stereoscopic viewing system using mounted projection

A method of classifying an individual's personal preference for an image, comprising: viewing an image for a period of time; and ranking the image on a scale extending between a &ldquo;detached&rdquo; feeling and an &ldquo;attached&rdquo; feeling, where &ldquo;detached&rdquo; is a feeling of not being able to personally connect to the object or situation depicted in the image, and &ldquo;attached&rdquo; is a feeling of a personal connection to the object or situation depicted in their image.

Management of physiological and psychological state of an individual using images portable biosensor device

An organic electroluminescent display device that displays a preformed image includes spaced anode and cathode electrodes, organic electrically conductive hole transport layer and electron transport layer disposed between the anode and cathode electrodes, and a preformed image layer formed between the organic electrically conductive hole transport layer and electron transport layers such layer having a region that is preformed to have at least one preformed image such that when a voltage is applied across the anode and cathode electrodes which will cause a preformed image to be displayed. Voltages are applied across the anode and cathode electrodes of the organic electroluminescent display device causes the emission of light for viewing the preformed image.

Organic electroluminescent display device with performed images

A method of determining the physiological reactivity of an individual with respect to images, comprising: measuring at least one physiological parameter of an individual during a baseline calm period of time; measuring the said at least one physiological parameter of said individual during a stress period of time and a succeeding rest period of time; dividing said measured data for each of said periods of time into a plurality of predetermined time segments; computing a histogram or Fourier analysis as appropriate on said predetermined time segments for each said period of time; standardizing said computed data; conducting a principal component analysis, a canonical discriminant analysis, or a neural network, on said data to establish a baseline calm or rest period set of scores and a stress period set of scores; measuring the said at least one physiological parameter of said individual during an image presentation period of time; repeating said time segmenting, said histogram or Fourier analysis, and said standardizing steps on said measured physiological data for said image presentation period of time; applying said vectors from said conducting step to said image data to produce an image set of scores which are compared with said baseline and stress sets of scores; and determining whether said presented image is activating, deactivating, or neutral based on said comparison.

Management of physiological and psychological state of an individual using images biometric analyzer

Growing community of inventors

Rochester, NY, United States of America

Jose M Mir