Smithkline Beecham Corporation

Glaxosmithkline LLC

Jose J Conde

Marvin Sungwhan Yu

Michael Anthony McGuire

Susan C Shilcrat

Matthew Allen Zajac

John Anthony Kowalski

Michael D Wallace

Lewilynn L Goldfinger

Anthony John Kowalski

The present invention is a process comprising contacting a compound of formula 6: or a pharmaceutically acceptable salt thereof;with a deprotecting reagent to form a compound of formula A: or a pharmaceutically acceptable salt thereof;where R is H or OR; Rand each Rare protecting groups; Ris H or OH, and n is 0, 1, 2, 3, 4 , or 5.

Process for preparing benzoxaboroles

Disclosed is a new process and intermediates for preparing benzazepines of Formula (I): wherein Rand Rare as defined herein.

Process and intermediates for preparing benzazepines

Herein is provided a process for preparing substituted cyclohexanoic acids of formula (I), where R is a carbon-containing group optionally linked by oxygen, sulfur or nitrogen to the phenyl ring and j is 1-5; and one of R and R* is hydrogen and the other is C(O)OH.

Process and intermediates for making 4-cyanosubstituted cyclohexanoic acids

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King of Prussia, PA, United States of America

Jose J Conde