Ferrer Internacional, S.a.

Jos&eacute; A Ortiz

Rafael Foguet

Aurelio Sacristan

Josep M Castello

Jordi Bolos

Jordi Bol&oacute;s

Josep M Castell&oacute;

Aurelio Sacrist&aacute;n

3-(Hydroxymethyl)chromen-4-ones of formula (I) are described and a process for preparing said compounds. The process consists in reacting the compounds of general formula (II) wherein R is hydrogen, halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms optionally substituted by phenyl or halogen, with formaldehyde and a basic catalyst followed by dehydration in an acid medium to form 3-(hydroxymethyl)chromen-4-ones of general formula (I), wherein R is as defined for (II);

Process for preparing 3-hydroxymethyl chromen-4-ones

7-&lsqb;3-&lsqb;4-(6-Fluorobenzo&lsqb;d&rsqb;isoxazol-3-yl)piperidin-1-yl&rsqb;propoxy&rsqb;-chromen-4-one derivatives having the formula (I):

7-&lsqb;(Piperidin-1-YL)-Propoxy&rsqb;-chromen-4-one derivatives, their preparation and their pharmaceutical use

Growing community of inventors

Barcelona, Spain

José A Ortiz

Growing community of inventors

Barcelona, Spain

Jos&eacute; A Ortiz

José A Ortiz