Academisch Ziekenhuis Leiden

Universiteit Maastricht

Xeltis B.v.

Academisch Ziekenhuis Leiden (h.o.d.n. Leids Universitair Medisch Centrum)

Joris Ivo Rotmans

Martijn Antonius Johannes Cox

Clemens Antoni Van Blitterswijk

Tom Lavrijsen

Lorenzo Moroni

Febriyani Fiain Rochel Damanik

Tonia Caroline Rothuizen

Antonius Johannes Rabelink

Koen Elzert Adriaan Van Der Bogt

Wouter Jan Geelhoed

A subcutaneous arteriovenous graft system includes an arteriovenous graft having an arterial end, a venous end opposite to the arterial end and an internal volume between the arterial end and the venous end, and a valve device that can be arranged in an open state, in which fluid flow through the graft is possible and a closed state in which the fluid flow through the arteriovenous graft is blocked. The valve device is constructed to decrease, in the closed state of the valve device, the internal volume of the complete graft to substantially zero.

Arteriovenous graft system, arteriovenous valve device and method to implant an arteriovenous graft system

The present disclosure relates to in situ tissue engineering, more specifically in situ vascular tissue engineering with the aim of providing a tissue structure which can be used e.g. as a substitute blood vessel or as a blood vessel functioning as cannulation site in hemodialysis. In particular, the disclosure involves tissue structure formation around a subcutaneously implanted synthetic rod. In addition, the disclosure involves a method for producing said synthetic rod.

In situ tissue engineering

Growing community of inventors

Leiden, Netherlands

Joris Ivo Rotmans