H. Lundbeck A/s

Jorgen Brodersen

Michael Harold Rock

Morten Jorgensen

Andre Faldt

Michael J Mealy

Lone Munch Ringgaard

This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl) -phenyl]piperazine or a pharmaceutically acceptable salt thereof. The process includes reacting compound II with compound III and compound IV in the presence of a solvent, a base and a palladium catalyst. R, R', X, and Xin the formulas above are defined in the Specification.

Process for preparing 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or pharmaceutically acceptable salt thereof

This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a salt thereof. The process includes reacting compound II with compound III and compound IV in the presence of a solvent, a base and a palladium catalyst. R, R', X, and Xin the formulas above are defined in the Specification.

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Holbaek, Denmark

Jorgen Brodersen