Lumicell, Inc.

Massachusetts Institute of Technology

Duke University

Jorge M Ferrer

W David Lee

Moungi G Bawendi

David B Strasfeld

David G Kirsch

Lisa F Marshall

The present invention provides compositions and methods for imaging tumor resections.

Methods and systems for spatially identifying abnormal cells

Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, the image analysis system collects a surgical site image and indicates on a display one or more locations of the identified cancer cells. In some embodiments, the method for identifying residual cancer cells comprises determining and selecting a portion of the surgical site image responsive to an intensity parameter; modifying the selected portion of the surgical site image to determine one or more groups of residual cancer cells based on size; and identifying at least one of the one or more groups of residual cancer cells from the modified portion of the surgical site image using a local-based threshold.

System and method for residual cancer cell detection

A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.

System and method for large field of view, single cell analysis

Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.

Medical imaging device and methods of use

The invention provides systems and method for the removal of diseased cells during surgery.

Methods and system for image guided cell ablation

Methods and system for image guided cell ablation with microscopic resolution

The present invention provides compositions and methods for imaging, for example, tumor resections.

Growing community of inventors

Cambridge, MA, United States of America

Jorge M Ferrer