Asta-werke Aktiengesellschaft

Asta Pharma Aktiengesellschaft

Asta-werke Aktiengesellschaft, Chemische Fabrik

Asta Pharma Aktiengesellshaft

Jorg Pohl

Gerhard Scheffler

Norbert Brock

Ulf Niemeyer

Peter Emig

Hans Pohle

Hans-Dieter Lenke

Jurgen Engel

Peter Hilgard

Wolfgang Schumacher

Rainer Voegeli

Johannes Respondek

1,2-Bis(aminomethyl)-cyclobutane-platinum complexes having an anti-tumor activity.

1,2-bis (aminomethyl) cyclobutane-platinum complexes

This invention relates to new oxzaphosphorin-4-thio-alkanesulphonic acids and to the neutral salts thereof corresponding to the general formula I ##STR1## and to methods to use such compounds to treat cancer diseases and to produce immunosuppression in humans and animals.

oxazaphosphorin-4-thio alkanesulphonic acids, neutral salts thereof and

This invention relates to new oxazaphosphorin-4-thio-alkanesulphonic acids and to the neutral salts thereof corresponding to the general formula I ##STR1## and to methods to use such compounds to control cancer diseases and to produce immunosuppression in humans and animals.

Oxazaphosphorin-4-thio-alkanesulphonic acids, and neutral salts thereof

The present invention relates to new 4-carbamoyloxy-oxazaphosphorins of the general Formula I ##STR1## as well as to a method for the treatment of malign tumor diseases in humans using such compounds as active agent.

4-carbamoyloxy-oxazaphosphorins

Process for the treatment of spasmodic conditions in humans by administering a compound of the general formula ##STR1## or a pharmacologically acceptable acid addition salt thereof to a human suffering from such conditions.

Process for the treatment of spasmodic conditions in humans

The present invention is related to new basic enol ethers having the general formula ##STR1## and to the pharmacologically acceptable acid addition salts thereof. The invention is further related to process for the treatment of spasmodic conditions in humans by administering a compound of the above general formula or a pharmacologically acceptable acid addition salt thereof to a human suffering from such conditions.

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Halle, Germany

Jorg Pohl