Bayer Aktiengesellschaft

Jorg Pfitzner

Karl G Metzger

Delf Schmidt

Gunter Benz

Theo Schroder

Hans-Joachim Zeiler

Horst Weyland

Rolf Dhein

Hans Rudolph

Knud Reuter

Martin Scheer

Wolfgang Gau

Klaus Bauer

Wilfried Kaufmann

New antibiotics of the formula ##STR1## in which X is O or N--CO--NH.sub.2,

New antibiotics, preparation and use of and intermediates therefor

Antibiotics, preparation and use of and intermediates therefor

An antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (B) as described herein. The compound possesses antimicrobial activity. Also fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infection.

Streptomyces species and process for producing antibiotic

The invention relates to antimicrobial compounds of Formula (I) and semi-synthetic methods for their production. Also included in the invention are compositions containing said antimicrobial compounds and methods for the use of said compound and compositions.

Antibiotic compounds, their production and their medicinal use

The invention relates to an antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (A) as described herein. The compound possesses antimicrobial activity. Also included in the invention are fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, the invention includes pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infections.

Antibiotic compound, its production and its medicinal use

The invention relates to an antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (B) as described herein. The compound posesses antimicrobial activity. Also included in the invention are fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, the invention includes pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infection.

Polyesters having a hydroxyl number of from 50 to 400 and containing 20 to 90% by weight of co-condensed .beta.-hydroxybutyric acid units have proved to yield transparent, glossy, elastic and hard coatings.

.beta.-Hydroxybutyric acid polyesters, a process for their production

The invention relates to the provision of an antimicrobial antibiotic obtained by culturing Actinoplanes strain ATCC 31440 under aerobic conditions in the presence of sources of carbon and nitrogen and in the presence of trace amounts of minerals. In addition to their use as antimicrobials, the antibiotics of the invention can be used for improving the growth and feed utilization in animals.

Growing community of inventors

Wuppertal, Germany

Jorg Pfitzner