Valneva Austria Gmbh

Intercell Ag

Jörg Fritz

Michael Buschle

Frank Mattner

Wolfgang Zauner

Eszter Nagy

Karen Lingnau

Alena Egyed

André Habel

Karin Prinz

The invention relates to a vaccine which comprises at least one antigen and a peptide comprising a sequence R&#x2014;XZXZXZX&#x2014;R, whereby N is a whole number between 3 and 7, preferably 5, X is a positively charged natural and/or non-natural amino acid residue, Z is an amino acid residue selected from the group consisting of L, V, I, F and/or W, and Rand Rare selected independently one from the other from the group consisting of &#x2014;H, &#x2014;NH, &#x2014;COCH, &#x2014;COH, a peptide with up to 20 amino acid residues or a peptide reactive group or a peptide linker with or without a peptide; X&#x2014;Rmay also be an amide, ester or thioester of the C-terminal amino acid residue, as well as the use of said peptide for enhancing a patient's adaptive immune response to an antigen.

Vaccine composition comprising an antigen and a peptide having adjuvant properties

The invention refers an improved vaccine against infections with pathogens, especially viral pathogens, comprising an antigen, a peptide of the formula R&#x2014;XZSZ&#x2014;XZX&#x2014;Rand an immunostimulatory deoxynucleic acid containing deoxyinosine and/or deoxyuridine residues.

Vaccines comprising an immunostimulatory peptide and an immunostimulatory oligodeoxynucleic acid molecule

The invention relates to a vaccine which comprises at least one antigen and a peptide comprising a sequence R&#x2014;XZXZXZX&#x2014;R, whereby

Described is a vaccine which comprises at least one antigen and at least one cathelicidin derived antimicrobial peptide or a derivative thereof as well as the use of a cathelicidin derived antimicrobial peptide or a derivative thereof for the preparation of an adjuvant for enhancing the immune response to at least one antigen.

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Vienna, Austria

Jörg Fritz