Basf Aktiengesellschaft

Bds Pharma Gmbh

Basf Aktiengesellschaft and Schenk Filterbau Gmbh

Jorg Breitenbach

Joerg Rosenberg

Axel Sanner

Werner Maier

Siegfried Lang

Sven Grabowski

Helmut Fricke

Hans D Zettler

Bernhard Fussnegger

Stefan Stein

Michael Schiessl

Son Nguyen Kim

Bernd Liepold

Herbert Fisch

Horst Baumgartl

Jurgen Hofmann

Karin Sperling

Karin Sperling-Vietmeier

Peter Hossel

Dietmar Oechsle

Jens Rieger

Andreas Kleinke

Didier Lefebvre

Peter Hölig

Wolfgang F Muller

Benedikt Steitz

Steffen Bossmann

Axel Paul Hartl

Dietrich Thoma

Jurgen Zeidler

Hans-Bernd Reich

A delivery system for sustained release of a calcium-channel blocking agent is adapted for introduction in the cerebrospinal fluid of a subject. The delivery system comprises a solid dispersion product of a calcium-channel blocking agent in a mixture of a (i) first poly(lactide-co-glycolide) having a molecular weight distribution centered around a first number average molecular weight Mnand a (ii) second poly(lactide-co-glycolide) having a molecular weight distribution centered around a second number average molecular weight Mn, wherein Mnis in the range of from 2000 to 3000 g/mol and the ratio of Mn/Mnis from 1.8 to 3.5. The delivery system is deposited in the vicinity of or adjacent to a blood vessel showing vasospasm or suspected of developing vasospasm.

Delivery system for sustained release of a calcium-channel blocking agent

Solid foamed active substance preparations

Production of lenticular tablets by melt calendering

Method of producing multi-layer medicaments in solid form for oral or

Depth-type filter for killing microorganisms and inactivating viruses

Transparent rapid release compositions of non-steroidal analgesics

Solid drug forms are produced by mixing and melting at least one pharmacologically acceptable polymeric binder and at least one pharmaceutical active ingredient, with or without conventional pharmaceutical additives, in the absence of a solvent to give a plastic mixture and shaping the mixture to the required drug form by extrusion, where the shaping takes place in two steps, with the extrudate being broken into shaped articles in a first step, and these shaped articles being rounded off in a second step in the plastic state.

Production of solid drug forms

The present invention relates to the use of polyamides in cosmetics which carry sulfonate groups and are obtainable from

Cosmetic compositions comprising sulfonate groups containing polyamides

Process and apparatus for the production of divisible tablets

A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least one solid product, which may contain an active ingredient incorporated into the still plastic composition during the molding step.

Process for producing solid drug forms having at least two phases

Polymer complexes which comprises hydrogen peroxide, a polymer suitable for complex formation with hydrogen peroxide, and at least one metal colloid and/or metal salt are prepared as described and used in bactericidal compositions, disinfectant systems, hair cosmetic compositions and as free-radical initiators for chemical reactions.

Polymer/hydrogen peroxide complexes

Storage-stable drug form

Solid active extrusion compound preparations containing low-substituted

Growing community of inventors

Mannheim, Germany

Jorg Breitenbach