Medichem, S.a.

Jordi Bosch Llad&oacute;

Maria Del Carmen Onrubia Miguel

Elias Molins Grau

Alberto Stampa Diez Del Corral

Eug&egrave;nia Pagans Lista

M&agrave; Del Carmen Onrubia Miguel

Rafael Garc&iacute;a Cruz

The invention describes a process for the preparation of pharmaceutical grade gabapentin, consisting of neutralizing an alcoholic solution of gabapentin hydrochloride with basic ion exchange resins and thereafter directly isolating the gabapentin, without requiring either the formation or the isolation of intermediates other than the pharmaceutical grade product.

Process for producing gabapentin or pharmaceutical grade

The non-hydrated gabapentin polymorph is prepared by drying an aqueous solution of gabapentin by spray drying or turbo-drying and it is used for the preparation of pharmaceutical grade gabapentin by subjecting the polymorph to crystallisation from solvents.

Non-hydrated gabapentine polymorph, production process and utilization for producing pharmaceutical grade gabapentine

The form B of paroxetine maleate polymorph is characterized by determined data of X ray diffraction: it has a chemical stability which is superior to that of the form A of paroxetine maleate. This superior stability enables to use the new polymorph for the fabrication of medicaments intended to the treatment of troubles related to dysfunctions of the central nervous system. The process for producing the paroxetine maleate comprises the preparation of paroxetine maleate solution and a consequent precipitation.

Growing community of inventors

Gerona, Spain

Jordi Bosch Lladó

Growing community of inventors

Gerona, Spain

Jordi Bosch Llad&oacute;

Jordi Bosch Lladó