Grifols, S.a.

Grifols Worldwide Operations Limited

Grifols Engineering, S.a.

Jordi Boira Bonhora

Carlos Roura Salietti

Daniel Fleta Coit

Miquel Faba Vilella

Carlos Roura Fernandez

Victor Grifols Roura

David Pages Becerra

Oriol Casanova Montpeyo

Sergi Roura Adell

Jose Coca Garrote

A system for dispensing a liquid in a closed chamber includes at least one rapid transfer port in at least one wall of the closed chamber. In addition, a liquid is dispensed in a closed chamber that includes at least one rapid transfer port in at least one wall of the closed chamber.

System and method for dispensing a liquid in a closed chamber

A system for the sterile filling of containers for pharmaceutical products, which includes a device for sterilizing containers and a machine for filling sterilized containers, wherein the device for sterilizing containers includes at least one autoclave, and wherein the system includes an automated container-accumulation device and means for automatically transporting the containers sterilized in the autoclave from said autoclave to the container-filling machine via said container-accumulation device.

System and method for the sterile filling of containers

Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.

Method for the aseptic filling of a bag

An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

Device and method for sterilizing flexible bags by electron beam irradiation

A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

Method for sterilizing flexible bags

A container for sterilizing flexible bags can be for pharmaceutical use. The container includes an upper flat structure including at least one element supporting the flexible bags and designed to accommodate a plug port of the flexible bag. The support element includes at least one fastening element, which is suitable for retaining the flexible bags once they are inserted into the support element. The container also includes a lower receptacle designed to contain the upper flat structure and to couple to the upper flat structure in a detachable manner. The container further includes a cap for hermetically sealing the lower receptacle.

Container for sterilizing flexible bags

A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

Device for sterilization of flexible bags and method for sterilizing flexible bags

An automatic device for emptying bags of frozen blood product includes a product removal device, a product reception hopper, a transporter for transporting the bag from a reception area to the product removal device, and at least one cutter located in the path of the bag between the reception area and the product removal device. The at least one cutter is housed in a support configured to oscillate for absorbing energy of impacts of the bag against the cutter and to return the cutter to its initial position.

Automatic device for emptying bags of frozen blood product

A method and device detect defects in the closure of encapsulated vials. The method includes scanning a profile of the capsule and of the vial using a profilometer, thus obtaining a point cloud. From the point cloud obtained, calculating at least one of the following parameters: diameter or radius of the closure circumference of the capsule; angle of intersection between the lower skirt and the side of the capsule; length of the lower skirt; and/or a distance from the end of the lower skirt to the neck of the vial. The method determines whether any of the parameters calculated in the previous step exceeds a predetermined value. The device detecting defects in the closure of encapsulated vials includes a profilometer configured to scan a profile of the capsule and of the vial and a control device configured to execute the method.

Method and device for detecting defects in the closure of encapsulated vials

An RFID tag is for arrangement on a bottle for blood-derived products. The bottle includes a main body, the upper end of which includes a neck. The bottle is hermetically sealed by a cap arranged in the upper portion of the neck. The upper portion of the cap includes at least two through-pipes and at least two stiffening ribs that are each connected to the pipes by one of the respective ends thereof. The RFID tag has at least two openings shaped to fit each of the through-pipes, respectively, of the cap such that said RFID tag is positioned on the upper surface of the cap and thus overcomes the obstacle of the through-pipes and the respective stiffening ribs.

RFID tag for its arrangement on a blood-derivated products bottle and use of the same

A hermetically-sealed plastics container for blood derivative products is provided. The container may have an internal surface and an external surface, characterized in that it comprises an RFID inlay between the internal surface and the external surface.

Container for blood derivative products

A process for filling pharmaceutical product containers in a container filling machine with the stages of: filling the container with the corresponding pharmaceutical substance through filling means in a filling station of the filling machine, weighing the filled container in a filled container weighing station to confirm that the quantity of pharmaceutical substance with which the container has been filled lies within the desired range, in which when the quantity of pharmaceutical substance with which the container has been filled lies outside the desired range the filling means are moved to the filled container weighing station and the container is topped up with a quantity such that the total substance placed in the container in the two stages lies within the desired range.

Machine and method for filling pharmaceutical product containers

Device for emptying a bag containing a frozen blood-derived product, including: a cutting device; an extractor for the product, a hopper for receiving the product, a device for transporting the bag from a receiving area to the plasma extractor, this transporting device including a robotic arm with a gripper which, in turn, includes: two catching arms, each defining at least a distal end and a proximal end, and an actuator, in which the actuator controls a mechanism for modifying the distance separating the distal ends of the gripper arms to catch the bag by its lower surface.

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Terrassa, Spain

Jordi Boira Bonhora