Bruker Biospin Gmbh

Bruker Biospin Ag

University of York

Joost A B Lohman

Joerg Hinderer

Werner E Maas

Dirk Wilhelm

Simon Benedict Duckett

Antonio Giuseppe Gianotti

Hannes Grubinger

Sami Antoine Adrien Jannin

Gary George Reginald Green

A DNP apparatus includes a cryostat () having an opening () and a loading path for a sample (), the loading path extending from the opening to a sample receptacle (), with a cryomagnet and a microwave source () as well as a configuration for supplying microwave radiation from the microwave source to the sample, which comprises a microwave path extending directly to the sample. The microwave path extends spatially separately from the loading path and the configuration for supplying microwave radiation has at least one microwave feed-through passing through one or more walls of the cryostat. The microwave path is incident on the sample from a direction opposite to the loading path or from a sideward direction at right angles to or at an inclination with respect to the axis of the loading path. This leads to simple and efficient polarization of the electron spins in the sample.

DNP apparatus

A method and apparatus for producing a hyperpolarized sample material for use in an NMR investigation provides for a cryogenic region having a target material containing a first hyperpolarizable nuclear species, a second hyperpolarizable nuclear species, and a nuclear spin polarizing agent, wherein the first nuclear species has a higher magnetic moment than the second nuclear species. Microwave energy is used to excite electron spin transitions in the polarizing agent in the presence of a magnetic field. The first hyperpolarizable nuclear species is thereby caused to interact with the electron spin system in the polarizing agent and generate hyperpolarization of at least the first nuclear species of the target material. The target material is then subjected to a lowered magnetic field, wherein the lowered magnetic field facilitates polarization transfer by nuclear thermal mixing between the species to thereby hyperpolarize the second nuclear species.

Device and method for rapid dynamic nuclear polarization

Growing community of inventors

Kenilworth, United Kingdom

Joost A B Lohman