Posco

Postech Foundation

Pohang University of Science and Technology Foundation

Joon-Won Park

Bong-Jin Hong

Hong-Jin Kim

The present invention relates to a method for the synthesis of a polynucleotide on a modified surface of a substrate, wherein the modified surface is obtained by chemically modifying with macromolecules in which a plurality of termini of the branched region are bound to the surface and a terminus of the linear region is functionalized.

Polynucleotide synthesis on a modified surface

Provided is a method for forming solid substrates having high density of primary amine group on its surface, in which the primary amine groups on the surface of an aminosilylated substrate are treated with aziridine or an aziridine derivative. The surface density of the primary amine functional groups (&mdash;NH ) on the very top surface of a substrate can be drastically increased.

Growing community of inventors

Pohang, South Korea

Joon-Won Park