Japan Science and Technology Agency

The University of Tokyo

Joon-Sik Park

Kazunori Kataoka

Yuichi Yamasaki

Shigeto Fukushima

Kensuke Osada

Aya Koide

The present invention discloses a vesicle which is excellent in structure stability and environmental responsiveness and also can be produced by a simple operation. More particularly, the present invention discloses a vesicle comprising a membrane formed of a first block copolymer containing a non-chargeable hydrophilic segment and a chargeable segment, and a second block copolymer containing a non-chargeable hydrophilic segment and a chargeable segment having an electric charge which is opposite to that of the chargeable segment of the first block copolymer.

Electrostatically bonded polymer vesicle

The invention provides approximately monodispersible random copolymers obtained from monomeric mixtures of 2-ethyl-2-oxazoline with 2-isopropyl-2-oxazoline, production method thereof and 2-isopropyl-2-oxazoline homopolymer obtained by using special initiator. Such polymers exhibit temperature-responsiveness in an aqueous solution within a broad temperature range, and are useful materials in the technical fields of surface chemistry and biomaterials.

Random copolymers of oxazoline

Growing community of inventors

Tokyo-to, Japan

Joon-Sik Park