Life Technologies Corporation

Applied Biosystems, LLC

Joon Mo Yang

David M Liu

Mark F Oldham

Charles Stuart Vann

Joy Roy

Dennis Lehto

Ian A Harding

Nigel P Beard

Yuh-Min Chiang

Umberto Ulmanella

Alexander A Dromaretsky

Sergey V Ermakov

John R Van Camp

Maryam Shariati

Min Yue

Jon A Hoshizaki

Patrick D Kinney

Steven W Sherwood

Aldrich Lau

Huan L Phan

Michele Elizabeth Wisniewski

Hans Fuernkranz

John Van Camp

Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.

Systems and methods for multiple analyte detection

A method for sorting cells in a biological sample comprising a first type of cells and a second type of cells may comprise introducing the biological sample into a chamber comprising a first surface and a second surface, wherein the first surface is associated with a transparent electrode and the second surface is associated with a photoconductive portion of an electrode. The method may further comprise moving incident light and the photoconductive portion relative to one another so as to illuminate regions of the photoconductive portion and modulate an electric field in the chamber in proximity to the illuminated regions. The method may further comprise separating the first type of cells from the second type of cells in the chamber via dielectrophoretic movement of the first type of cells and the second type of cells caused by the modulated electric field, wherein a dielectrophoretic characteristic of at least one of the first type of cells and the second type of cells has been modified.

Devices and methods for optoelectronic manipulation of small particles

Assemblies for and methods of coupling a microtiter plate and receptacle for centrifugation of liquid from the microtiter plate to the receptacle are provided. In some embodiments, a coupling frame can be used. In other embodiments, the microtiter plate couples directly to the receptacle. In some embodiments, relative motion between the receptacle and the microtiter plate is limited in the x-y plane. In some embodiments, relative motion between the receptacle and the microtiter plate is limited in the x-z plane. In some embodiments, relative motion between the receptacle and the microtiter plate is limited in the y-z plane.

Methods and assemblies for collecting liquid by centrifugation

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Redwood City, CA, United States of America

Joon Mo Yang