Samsung Electronics Co., Ltd.

Jongsuk Chung

Jongmyeon Park

Eunjin Lee

Jeonggun Lee

Tae Jin Ahn

Dae-Soon Son

A method of predicting an effect of an anti-c-Met antibody and/or selecting a subject for application of an anti-c-Met antibody including measuring a level of the biomarker in a biological sample, is provided.

Biomarker for predicting effect of an anti-c-Met antibody

Provided are a valve unit, a microfluidic device including the same, and a method of fabricating the valve unit. The method includes: forming a lower substrate including a channel including a first region and a second region which is deeper than the first region and is adjacent to one side of the first region; forming an upper substrate comprising a valve material chamber which extends only partially through the upper substrate; filling the valve material chamber with a valve material and curing the valve material in the valve material chamber; attaching a surface of the upper substrate in which the valve material chamber is formed to a surface of the lower substrate in which the channel is formed, so that the valve material chamber overlaps an overlapped portion of the first region, and does not overlap a non-overlapped portion of the first region; melting the valve material accommodated in the valve material chamber to flow the valve material into the non-overlapped portion of the first region; and curing the valve material flowed into the non-overlapped portion to close the first region.

Growing community of inventors

Hwaseong-si, South Korea

Jongsuk Chung