Seoul National University

Jong-Wan Park

Yeo-Chan Yoon

Sung-Chul Hohng

Hyoung Sook Park

Christoph Lienau

Kyeong-Hwa Yoo

Dai-Sik Kim

Yang-Sook Chun

Victor Malyarchuck

Han-Youl Ryu

Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for inhibiting adipocyte differentiation and a method for screening an adipocyte differentiation inhibitor using PPAR-v neddylation associated with adipocyte differentiation. The inhibitor of a neddylation pathway of PPAR-v inhibits the differentiation from mesenchymal stem cells to mast cells, and thus can be effectively used to treat obesity, and particularly, can be also useful in the treatment of severe obesity which cannot be excepted to be treated by existing obesity treatment agents.

Methods for suppressing adipocyte differentiation

Disclosed is a surface plasmon optic device that has a periodic array of apertures in a dielectric substrate and a metal film formed on the dielectric substrate and emits light from metal-air interface. The surface plasmon optic device includes a surface plasmon generating apparatus, a surface plasmon detecting apparatus, a surface plasmon controlling apparatus, an etching apparatus, etc. if a metal diffraction grating is disposed on the metal film having a well-defined interface, propagation of the surface plasmon can be efficiently reflected, divided and controlled. Further, radiating surface plasmon having a half period of a lattice constant formed at air-metal () can be preserved at a distance of at least a few micron.

Surface plasmon optic devices and radiating surface plasmon sources for photolithography

Growing community of inventors

Seoul, South Korea

Jong-Wan Park