Sk Chemicals Co., Ltd.

Coway Co., Ltd

Jong-Wan Kim

Hun-Taek Kim

Dae-Kee Kim

In-Young Song

Yong-Kook Kim

Jong-Il Ryu

Sang-Woo Kang

In-Seok Seo

Young-Gun Cho

Seong-Jin Yun

Ju-Hyun Baek

Chul-Soon Dan

An air purifier according to the present disclosure includes: a memory for storing a flow rate/pressure differential correlation graph with regard to each filter utilization state; a pressure differential sensor for measuring a pressure differential, which is a difference in pressure between the front and rear ends of the filter; and a filter replacement time management unit for determining the time to replace the filter according to a result of matching a pressure differential of the filter, which is measured by the pressure differential sensor at a preset cycle, and the flow rate of air flowing into the filter during pressure differential measurement with the flow rate/pressure differential correlation graph for each utilization state.

Air purifier, method for determining time to replace filter thereof, and device and method for determining filter replacement time pressure differential therefor

Disclosed is a method for producing proteins having factor VIII procoagulant activity in serum-free medium by in vitro culturing of mammalian cells, wherein the serum-free medium contains an inhibitor against the protease released from cultured cells. In accordance with this invention, the inhibitor can protect the cleavage of a target protein during cultivation and increase homogeneity of a target molecule, wherein the inhibitor can be a dextran sulfate. This invention also relates to a method of purifying target molecules from the culture medium containing both a target molecule and selected inhibitors by affinity chromatography.

Process for producing and purifying factor VIII and its derivatives

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Seoul, South Korea

Jong-Wan Kim