Osong Medical Innovation Foundation, Korea University Research and Business Foundation

Samsung Display Co., Ltd.

Jong-Uk Lee

Mun-Pyo Hong

Bo-Sung Kim

Sang Jun Sim

Min-Seong Ryu

Xingyi Ma

Woo-hyun Kim

The present invention relates to a nanoplasmonic biosensor capable of label-free multiplex detection of disease markers in blood with high selectivity and sensitivity and a method for detecting disease markers using the nanoplasmonic biosensor. The nanoplasmonic biosensor of the present invention enables label-free multiplex detection of miRNAs as disease markers in blood with high selectivity and sensitivity. Therefore, the nanoplasmonic biosensor of the present invention can be effectively used for the diagnosis of miRNA-related diseases and clinical applications.

Nanoplasmonic biosensor and method for detecting disease markers using the same

The present invention relates to a method for preparing metal nanostructures using DNA, and more particularly, to a method for preparing metal nanostructures, in which a self-assembling DNA is used as a frame, and thus the orientation, shape and size of the nanostructures are easily controlled compared to conventional bottom-up methods. Metal nanostructures prepared by the method show excellent localized surface plasmon resonance properties, and thus can be used as fluorescent substances in drug delivery, biomedical imaging, and supersensitive biosensors.

Method for preparing metal nanostructure based on biomolecules

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Seoul, South Korea

Jong-Uk Lee