Sk Chemicals Co., Ltd.

Jong-Seob Im

Bong-Yong Lee

Yeo-Jin Park

Joon-Gyo Oh

Jae-Sun Kim

Hun-Taek Kim

Won-No Youn

Won-Jae Choi

Yong Youn Hwang

Yong-Youn Hwang

Hye-Min Kim

Hae-In Rhee

Provided is a transdermal delivery system (for example, in the form of a patch) having a double-layer structure including a drug-containing matrix layer and an adhesive layer, wherein the drug-containing matrix layer is obtained by completely dissolving donepezil using a certain polymer and then formulating along with an adhesive; and a process for preparing the same. The transdermal delivery system according to the present invention does not show any crystallization of donepezil in the formulation, can release donepezil at a uniform rate for a long time, and can inhibit the release dumping phenomenon that occurs in a transdermal delivery system having a single-layer structure.

Percutaneous absorption preparation containing donepezil, and method for preparing same

Disclosed is a composition for transdermal administration containing tolterodine. The composition comprises lidocaine or a pharmaceutically acceptable salt thereof to achieve enhanced skin penetration. The composition enhances the skin penetration of tolterodine. Therefore, a successful commercial application of a tolterodine-containing transdermal preparation based on the composition can be expected.

Composition with improved skin penetration for transdermal delivery of tolterodine

Growing community of inventors

Gyeonggi-do, South Korea

Jong-Seob Im