California Institute of Technology

Jong Hwee Park

Matthew W Thomson

David Brown

Tatyana Dobreva

Lior S Pachter

Jase Gehring

Siyu Chen

The present disclosure provides methods, systems, devices, kits, and reagents for performing single cell sequencing (e.g., single cell RNA sequencing) from a low volume, capillary blood (or any low volume blood sample which is not obtained from a vein or by venipuncture).

Immune profiling using small volume blood samples

Disclosed herein include systems, methods, compositions, and kits for multiplexing single-cell RNA-sequencing (scRNA-seq) samples. In some embodiments, the methods comprise chemically tagging cells with identifying sample tags (e.g., barcoded DNA oligonucleotides).

Sample multiplexing for single-cell RNA sequencing

Growing community of inventors

Pasadena, CA, United States of America

Jong Hwee Park