Lg Display Co., Ltd.

Seoul National University

Yonsei University

Postech Academy-industry Foundation

Daewon Pharm., Co., Ltd.

Bexcore Co., Ltd.

Jong-Hoon Lim

Jung Hwan Lee

Seong-Wook Lee

Jong In Kim

Young-Joo Lee

Jeong-Hoon Lee

Sung Ho Ryu

Do-Yeon Kim

Eun Ju Oh

Tae-Rim Lee

Won Jun Kang

Seong Hui Jin

Jung Hwan Yoon

Kyung-Sook Shin

Sun-Yoon Kim

Sung-Won Lee

Chang-Ho Lee

A liquid crystal display device includes a first substrate; a thin film transistor on the first substrate; a first passivation layer on the thin film transistor; a first electrode on the first passivation layer; a second passivation layer on the first electrode; a second electrode of an oxide semiconductor on the second passivation layer; and an alignment layer on the second electrode. The second electrode includes first portions and second conductive portions alternating with the first portions. A surface of the first portions is flush with the second conductive portions.

Liquid crystal display device

The present invention relates to a DNA aptamer specifically binding to a hepatocellular carcinoma-related Glypican-3 (GPC3) protein, treatment of cancers related to the Glypican-3 protein using the same, a composition for inhibiting a cancer and a composition for diagnosing a cancer comprising the same as an active ingredient.

Glypican-3 specific aptamer and use thereof

Disclosed is a nuclease-resistant RNA aptamer for inhibiting the replication of HCV replicon. This aptamer is capable of binding specifically to HCV NS5B and inhibiting the proliferation of the HCV replicon, and includes at least one sequence selected from a group consisting of SEQ ID NOS. 1 to 4, in which a fluoro group is substituted for 2'-hydroxy of both U (uracil) and C (cytosine) bases, and SEQ ID NO. 17, in which the fluoro group is substituted for the 2&#x2032;-hydroxy of both the U (uracil) and the C (cytosine) bases, and which is tagged with a cholesteryl group at a 5&#x2032; end and with idT at a 3&#x2032; end. The RNA aptamer is useful in the diagnosis and treatment of HCV infection.

Nuclease-resistant RNA aptamer inhibiting replication of hepatitis C virus replicon

Growing community of inventors

Seoul, South Korea

Jong-Hoon Lim