Pohang University of Science and Technology Foundation

Jong Hoon Hahn

Bong Chu Shim

Kyung Won Ro

Young Chan Kim

Yong Min Park

Kwanseop Lim

A high-efficiency, high-sensitivity absorbance detection system in a lab-on-a-chip is provided. The absorbance detection system includes detection cells having an optical pathlength ten times and/or much longer than the width of a separation channel to improve detection sensitivity, lens structures for collimating light in the detection cells, and slit structures for preventing scattered light from entering detectors. The detection cells, the lens structures, and the slit structures of the absorbance detection system are fabricated and integrated in a lab-on-a-chip. The absorbance detection system exhibits excellent absorption efficiency, detection limit, and linearity, compared to existing absorbance detection systems, and can be applied for the detection of a variety of samples. The absorbance detection system does not need labeling of the samples which saves time and costs. The absorbance detection system can be used effectively in detecting trace compounds with a high sensitivity. The absorbance detection system in a lab-on-a-chip can be used with wider applications to a variety of samples in diverse research fields, such as the drug screening field dealing with simultaneous synthesis and identification of a number of compounds based on combinatorial chemistry, the life sciences field handling trace bioactive materials such as enzymes, proteins, and amino acids, and the environmental research field which needs rapid field monitoring of contaminants.

Absorbance detection system for lab-on-a-chip

A process, which comprises forming a metal micro-pattern on the surface of an inorganic substrate, surface-treating the surface of the metal micro-pattern and the surface of the plastic substrate to make it chemically reactive, and bringing the metal micro-pattern into contact with the surface of the plastic substrate to transfer the metal micro-pattern from the surface of the inorganic substrate to the surface of the plastic substrate, can be easily and simply carried out using conventional equipments to produce one or more metal pattern fixed on a plastic material.

Growing community of inventors

Pohang, South Korea

Jong Hoon Hahn