Eyenovia, Inc.

Physical Devices, LLC

Other

Jonathan Ryan Wilkerson

Charles Eric Hunter

Iyam Lynch

Joshua Richard Brown

Frederick Vosburgh

Louis Thomas Germinario

J Sid Clements

Charley Theodore Wilson, Iii

Bernard L Ballou, Jr

Kris Grube

James Thornhill Leath

Nathan R Faulks

Peter Lam

Jeffrey Parrott

Lucien S Wilkins

Hamilton Coleman

Matthew Ditrolio

Bernard L Ballou

Coleman Hamilton

Lucien S Wilkens

Lyam Lynch

The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Spray ejector mechanisms and devices providing charge isolation and controllable droplet charge, and low dosage volume ophthalmic administration

An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Spray ejector device and methods of use

In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

Ejector devices, methods, drivers, and circuits therefor

An ejector device and method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use is disclosed. The ejector device includes a housing, a reservoir disposed within the housing for receiving a volume of fluid, and an ejector mechanism in fluid communication with the reservoir and configured to eject a stream of droplets, the ejector mechanism comprising an ejector plate coupled to a generator plate and a piezoelectric actuator; the piezoelectric actuator being operable to oscillate the ejector plate, and thereby the generator plate, at a frequency and generate a directed stream of droplets.

Ejector mechanism, ejector device, and methods of use

High modulus polymeric ejector mechanism, ejector device, and methods of use

An invention for rapid chilling or heating of both carbonated and non-carbonated fluids is disclosed. The invention is a fluid dispensing device that can rapidly cool or heat carbonated or non-carbonated liquid from room temperature to a desired temperature. The electric on-demand device allows pour-through and pump-through fluid dispensing and temperature control.

System and method for rapid fluid chilling and heating for carbonated and non-carbonated fluids

Analog interference filter devices and methods for isolation of desirable portions of a radio frequency signal. Signal compensation is used to provide desirable center frequency, passband width, ripple, rolloff, stopband and distortion performance. The filter is implemented with passive and/or active components.

Tunable filter devices and methods

A piezoelectric ejector device is provided which is designed to minimize the intake of air into the device upon actuation by providing for laminar flow of the fluid. In an ejector mechanism that includes a generator plate and a piezoelectric actuator operable to directly or indirectly oscillate the generator plate, at a frequency to generate a directed stream of droplets of fluid, the generator plate includes a fluid facing surface, a droplet ejection surface, and a plurality of holes formed through its thickness between the surfaces. The plurality of holes are configured so as to minimize airflow through the plurality of openings from the droplet ejection surface to the fluid facing surface during generation of the directed stream of droplets by configuring the shape of the holes to minimize turbulence.

Laminar flow droplet generator device and methods of use

Methods, systems, and computer readable media for wideband frequency and bandwidth tunable filtering are disclosed. According to one aspect, the subject matter described herein includes a wideband frequency and bandwidth tunable filter that splits a filter input signal into first and second input signals, modifies the first input signal to produce a first output signal, modifies the second input signal to produce a second output signal having an intermediate frequency response, and combines the first and second output signals while adjusting their relative phases and/or amplitudes to produce a filter output signal with the target frequency response. Adjustment includes splitting the second input signal into third and fourth input signals, which are modified and then combined to produce the second output signal having the intermediate frequency response.

Methods, systems, and non-transitory computer readable media for wideband frequency and bandwidth tunable filtering

Growing community of inventors

Raleigh, NC, United States of America

Jonathan Ryan Wilkerson