University of Michigan

Other

University of Pittsburgh

General Electric Company

Endra Life Sciences Inc.

Jonathan M Rubin

J Brian Fowlkes

William F Weitzel

Kang Kim

James D Hamilton

Oliver Daniel Kripfgans

Matthew N O'Donnell

Jingping Xu

Jeffrey Brian Fowlkes

Srini Tridandapani

Joseph M Messana

Richard Yung Chiao

Michael M Thornton

Kai Erik Thomenius

Ray S Spratt

Paul Langford Carson

Jian-Feng Chen

Grant H Kruger

Charles Raymond Meyer

Aghapi Mordovanakis

Mainak Mitra

Benoit Desjardins

Xunchang Chen

Hua Xie

Theodore J Kolias

Theresa Ann Tuthill

Congxian Jia

Robert Brook

Anne Lindsey Hall

Leo Koziol

Aaron Moskalik

Brian Thelen

Ronald S Adler

A method of estimating lung motion includes collecting multiple ultrasound image data captured at one or more locations of a sample region of tissue. The method further includes comparing the multiple ultrasound image data and determining temporal correlation coefficients between each of the multiple ultrasound image data. The method still further includes displaying an image of the sample region of the tissue with the temporal correlation coefficients identified, thereby indicating lung motion. In further methods, the determined temporal correlation coefficients are used to determine an amount of decorrelation, which can be used to determine strain of the tissue over the sample region and to calculate lung displacements and lung shape changes representing ventilation.

Ultrasound speckle decorrelation estimation of lung motion and ventilation

A method of evaluating tissue stiffness of a target area includes positioning an ultrasound elasticity imaging apparatus adjacent a surface of an area of tissue where the target area is located and applying a dynamic range of force to the tissue. A plurality of ultrasound beams can be directed at the tissue and a plurality of ultrasound echoes can be acquired from the strained tissue in the target area to calculate an amount of developed strain within the target area.

Methods and apparatuses for measuring tissue stiffness changes using ultrasound elasticity imaging

An ultrasound imaging system uses a magnetic linear motor driven ultrasound scanner, with accurate track and hold operation and/or other motion feedback, to scan a two dimensional or three dimensional area of a sample. The scanner is implemented in a low-power and low-bandwidth handheld device and is connected with a remote image processing system that receives raw data and performs full ultrasound image analysis and creation, allowing the handheld to be used for scanning, pre-processing, and display.

Linear magnetic drive transducer for ultrasound imaging

A system and method for determining fractional fat content of tissue comprises registering thermoacoustic image coordinates to an acquired ultrasound image, the acquired ultrasound image at least comprising target tissue within a region of interest; defining a thermoacoustic voxel grid coincident with the region of interest; obtaining thermoacoustic image measurement values from tissue within the region of interest corresponding to the voxels within the defined thermoecoustic voxel grid to yield a thermoacoustic measurement matrix; normalizing the thermoacoustic image measurement values within the thermoacoustic measurement matrix; calculating a fractional fat content map for the target tissue within the region of interest based on the normalized thermoacoustic image measurement values within the thermoacoustic measurement matrix and a reference thermoacoustic measurement value; and correcting the fractional fat content map based on tissue speed-of-sound data to yield a final fractional fat content map for the target tissue within the region of interest.

Method and system for determining fractional fat content of tissue

An ultrasound-based system determines dynamic strain measurements over a surface using ultrasound speckle analysis that allows for accurate measurement of surface area displacement. The system additionally determines an approximate displacement along a third axis, the z-axis. From these, an estimation of a local volume change is determined. In this way, a volume change can be determined for the lung or any other region of interest.

Lung ventilation measurements using ultrasound

Lung ventillation measurements using ultrasound

Flexible cover for a calculator

An optimized elastic modulus reconstruction procedure can estimate the nonlinear elastic properties of vascular wall from intramural strain and pulse wave velocity (PWV) measurements. A noninvasive free-hand ultrasound scanning procedure is used to apply external force, comparable to the force in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. PWV is estimated at the same location where intramural strain is measured. The reconstructed elastic modulus is optimized and the arterial elastic modulus can be determined and monitored using a simple dual elastic modulus reconstruction procedure.

Measurement of tissue elastic modulus

An ultrasonic imaging system acquires echo signals from an object being imaged such as a moving coronary artery and the cross-correlation between echo signals is employed as an objective measure of relative object location. The method is used in a prescan procedure to determine an optimal gating window to acquire image data during a cardiac gated scan, and it is used during the scan as a real time gating signal.

Ultrasound gating of cardiac CT scans

Methods and systems for measuring mechanical property of a vascular wall and a method and system for determining health of a vascular structure are provided wherein local deformation of a vessel wall resulting from physiologic pressures with altered transmural forces is measured. A non-invasive free-hand ultrasound scanning-procedure was performed to apply external force, comparable to the force generated in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. When the applied pressure matched the internal baseline diastolic pressure, strain and strain rate increased by a factor of 10 over a cardiac cycle. Radial arterial strain was assessed in the vessel wall over the entire deformation procedure using a phase-sensitive, two-dimensional speckle-tracking algorithm. An elastic modulus reconstruction procedure was developed to estimate the non-linear elastic properties of the vascular wall.

Methods and systems for measuring mechanical property of a vascular wall and method and system for determining health of a vascular structure

An x-ray CT system performs a scan by acquiring projection views from which an image is reconstructed. In a prospective embodiment, the correlation of adjacent views is calculated as the scan is performed and is used to detect subject motion as the scan is being performed. In a retrospective embodiment, the correlation of adjacent views is calculated and is used to detect subject motion after the scan is completed. In the first embodiment substitute projection views are acquired by continuing the scan and in the second embodiment redundant projection views acquired during the scan are substituted until the best possible image is produced.

Projection gating of x-ray CT scan

The present invention is a miniature illuminating Christmas tree intended to create a decorative display in the window of a home, car, or office. In the preferred mode, the tree-shaped ornament is made from plastic and artificial green Christmas tree material and contains an illumination source, such as blinking LEDs, fiberoptics, or bulbs configured according to a previously determined pattern. A power source, such as at least one battery, is housed in the base or trunk of the ornament. The device is removably attached to a window through usage of one or more suction cups, and may be reversed, allowing the user to display the object on the outside or the inside of the window in question.

Miniature portable ornamental tree device

Growing community of inventors

Ann Arbor, MI, United States of America

Jonathan M Rubin