The General Hospital Corporation

The Broad Institute, Inc.

Jonathan Livny

Deborah Hung

Roby Bhattacharyya

Peijun Ma

The present disclosure relates to compositions, methods, and kits for rapid phenotypic detection of antibiotic resistance/susceptibility.

Compositions and methods for detecting antibiotic responsive mRNA expression signatures and uses thereof

The present disclosure relates to method of distinguishing between two or more species of one or more organisms in a sample, by contacting a biological sample comprising ribosomal ribonucleic acid (rRNA) with a set of antisense probes, wherein the set of probes contains at least one detectable probe that is specific for a target rRNA sequence of each species to be tested, and wherein the individual probes specific for each species comprises less than about 85% sequence identity; and, detecting hybridization between one or more of the probes and the rRNA, thereby distinguishing between two or more species in a sample.

Growing community of inventors

Cambridge, MA, United States of America

Jonathan Livny