United States of America As Represented by the Secretary of the Air Force

Jonathan L Kiel

Jill E Parker

Eric A Holwitt

John L Alls

Veronica Franz Sorola

The solutions provided here use DNA aptamers and quantum dots for the detection of bacteria, viruses, proteins or other targets. An example of a method described here comprises: providing a complex of DNA complementary strands, one strand being an aptamer, having one strand covalently linked to a quantum dot, and having the other strand linked to a quencher; and contacting the complex of DNA complementary strands with a microorganism or components thereof, under conditions that permit binding of the aptamer with the microorganism or components thereof.

Using DNA aptamers and quantum dots for the detection of proteins or other targets

E. coli strain JM109 transfected with nitrate reductase gene containing plasmid pIC20RNR1.1 produces diazoluminomelanin when cultured in a medium containing nitrate, 3-amino-L-tyrosine and luminol, under suitable metabolic conditions.

Diazodenitrification in manufacture of recombinant bacterial biosensors

A composition and process for suppressing the immune system of animals in which an effective amount of 3-aminotyrosine is administered which suppresses the endogenous immune system of animals.

Growing community of inventors

Universal City, TX, United States of America

Jonathan L Kiel