R.p. Scherer Corporation

Pharmacia Aktiebolag

Jonathan Kenneth Embleton

Peter John Houzego

Howard Norman Stevens

Sarah A Rocca

Luigi G Martini

Stephen P Jones

Richard J Malcolmson

Jonathan Ernest Lacy

Elizabeth A Perry

A unit container for a treatment fluid comprises a sealed enclosure of which one wall section thereof is formed with at least one opening. The enclosure is pressuriseable to discharge its contents through the opening or openings, which is or are of sufficient diameter to enable the generation of a jet and/or discrete droplets of treatment fluid discharged therefrom. The one wall section is typically a flat section of the enclosure wall, and the enclosure is typically a blister pack, with the wall section at a planar base of the blister. However, the one wall section may be dome-shaped and formed with at least one opening in the top region of the dome. Containers of the invention may be provided in packages, for example in strip form or in planar arrays. Dispensing devices are described for discharging their contents in treatment.

Ocular treatment device

This invention relates to pharmaceutical compositions for oral administration comprising a carrier and, as active ingredient, an ophthalmologically active compound, characterized in that the composition is formulated to promote pre-gastric absorption of the ophthalmologically active compound. A process for preparing such compositions and the use of such compositions for the treatment of ophthalmic diseases, particularly diseases caused by elevated intro-ocular pressure, such as ocular hypertension and glaucoma, are also provided.

Method for treating ophthalmic disease through fast dispersing dosage forms

There is provided a carrier for hydrophobic drugs, and pharmaceutical compositions based thereon, which carrier comprises a digestible oil and a pharmaceutically acceptable surfactant component for dispersing the oil in vivo upon administration of the carrier, which comprises a hydrophilic surfactant, said surfactant component being such as not to substantially inhibit the in vivo lipolysis of the digestible oil.

Delivery systems for hydrophobic drugs

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Berkshire, United Kingdom

Jonathan Kenneth Embleton