Optimer Pharmaceuticals, Inc.

Arena Pharmaceuticals, Inc.

Jonathan James Duffield

Youe-Kong Shue

Chan-Kou Hwang

Franklin W Okumu

Yoshitaka Ichikawa

Chi-Jen Frank Du

Mei-Chiao Wu

Yuan-Ting Chen

David Rabuka

Tawfik Gharbaoui

Ashwin M Krishnan

Dipanjan Sengupta

Yu-Hung Chiu

Yoshi Ichikawa

Alex Romero

Mark Macias

Ryan M Hart

Edward A Lally

Nainesh Shah

Kenneth Marby

Sulan Yao

Chang-Hsing Liang

Steve Sucheck

Ming-His Chiou

Ming-Hsi Chiou

Yoshiaki Ichikawa

Methods, processes and materials for the production and recovery of Tiacumicins produced by culturing a microorganism belonging to the speciessubspecieshaving the ability to produce and accumulate one or more Tiacumicin in a nutrient medium comprising a carbon source, a nitrogen source, trace elements such as inorganic salts, and an adsorbent, wherein said nitrogen source comprises fish powder, and wherein said Tiacumicin is produced in a yield greater than about 50 mg/L broth.

Tiacumicin production

The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HTserotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HTserotonin receptor modulators, compositions thereof and methods of using the same.

[object Object]

Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents.

Antibacterial agents

Described herein are novel macrolides, the preparation of novel macrolides, to the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents.

Growing community of inventors

San Diego, CA, United States of America

Jonathan James Duffield