Veracyte, Inc.

Jonathan I Wilde

Darya Chudova

Giulia C Kennedy

Eric T Wang

Hui Wang

Catalin Barbacioru

Moraima Pagan

Bonnie H Anderson

Nusrat Rabbee

James Diggans

Daniel Pankratz

Sharlene Velichko

James G Veitch

P Sean Walsh

Darya I Chudova

The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Methods for treatment of thyroid cancer

The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Methods for classification of tissue samples as positive or negative for cancer

Methods and compositions for diagnosis of thyroid conditions

Algorithms for disease diagnostics

Disclosed herein are kits, compositions, and methods relating to the classification of samples. Methods disclosed herein can be used to identify sample mix-ups. Methods disclosed herein can also be used to diagnose conditions or to support treatment-related decisions.

Methods and compositions for classification of samples

The present disclosure provides methods for processing or analyzing a sample of tissue of a subject, to generate a classification of the sample of tissue as positive or negative for thyroid cancer. The present disclosure also provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results.

Methods for processing or analyzing a sample of thyroid tissue

The present disorders disclosure provides method for processing or analyzing a sample of thyroid tissue of a subject, to generate a classification of the sample of thyroid tissue as positive or negative for thyroid cancer. The present disclosure also provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results, which may be used to provide a diagnosis.

Methods for processing or analyzing sample of thyroid tissue

The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Methods and compositions of molecular profiling for disease diagnostics

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Burlingame, CA, United States of America

Jonathan I Wilde