Dexcom, Inc.

Medivas, LLC

Jonathan Hughes

Peter C Simpson

Stephen J Vanslyke

Naresh Chandra Bhavaraju

Jeff Jackson

Rui Ma

Hari Hampapuram

Lauren Hruby Jepson

Leif N Bowman

Anna Leigh Davis

Huashi Zhang

Ted Tang Lee

Katherine Yerre Koehler

Robert James Boock

Matthew D Wightlin

Jason M Halac

Apurv Ullas Kamath

Jack Pryor

Jennifer Blackwell

Andrew Attila Pal

Phong Lieu

Ryan Everett Schoonmaker

Randall Scott Koplin

Arturo Garcia

Daiting Rong

Michael J Estes

Justen Deering England

Aditya Sagar Mandapaka

Maria Noel Brown Wells

Disha B Sheth

James R Petisce

Sebastian Böhm

David I-Chun Lee

Chris W Dring

Thomas Stuart Hamilton

Alexandra Lynn Carlton

Michael A Bloom

Mark Wu

David Sze

Philip Thomas Pupa

Becky L Clark

Jason Mitchell

David DeRenzy

Zebediah L McDaniel

Todd Andrew Newhouse

Timothy Joseph Goldsmith

Kyle G Neuser

Eric Gobrecht

Vincent Peter Crabtree

Leonard Darius Barbod

Liang Wang

Alexander Leroy Teeter

Zaza D Gomurashvili

Stefanie Lynn Mah

Jillian K Allen

Christopher M Davis

Kathleen Suzanne Hurst

Kyle Tinnell Keller

Jie Da

Neel Narayan Shah

Shanger Wang

Anna Leigh Rack-Gomer

Jiong Zou

James Jinwoo Lee

Devon M Headen

Apurv Ullas Karnath

Tim Ray Gackstetter

Roger Schneider

George Vigil

Kyle Neuser

Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

System and method for mode switching

Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

Automatic analyte sensor calibration and error detection

Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

Membrane for continuous analyte sensors

Systems and methods are disclosed which provide for a 'factory-calibrated' sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

System and method for factory calibration or reduced calibration of an indwelling sensor based on sensitivity profile and baseline model of sensors

The present disclosure relates to a needle including a wall structure, a cutting edge and a blunt contour. The needle advantageously can be used to deliver a sensor (such as a glucose or other analyte sensor) through an outer skin layer and into a sensor depth in a less invasive way than prior art needles. The size of the cutting edge is balanced against a portion of the distal wall structure that has blunt contours. Thus, the needle is capable of cutting the more durable outer skin layer (first phase) and then progressively stretching open the cut for further advancement into the subcutaneous layer (second phase). When the needle is sufficiently advanced, it is retracted leaving the sensor in a desired position. Early testing has shown a reduction of 'dip and recover' from glucose sensors delivered using the needle.

Needle for transcutaneous analyte sensor delivery

Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

Systems and methods for securing a continuous analyte sensor to a host

The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing. Systems and methods according to present principles allow for such steps to occur without significant loss of spring force, and without deleterious effects such as seal slingshotting.

Transcutaneous analyte sensors, applicators therefor, and associated methods

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Carlsbad, CA, United States of America

Jonathan Hughes