Fmc Corporation

Bayer Corporation

Jonathan H Morgan

Samuel Nochumson

Robert Allan Weinberg

Donald Walter Renn

Walter P Carney

Gail P Mazzara

Francis H Kirkpatrick

William C Snow

Sara J McKenzie

Foner P Curtis

Paula Jean Marks

David L Harper

Mikhail V Ostrovsky

Debra Ann Petit

This invention relates to a substantially purified p100 which is a human neu related protein having a molecular weight in the range from about 97,000 daltons to about 115,000 daltons which corresponds substantially to the extracellular domain of the human neu gene product, said protein being detectable in a biological fluid. In another embodiment this invention relates to assays for detecting this protein. Finally, this invention also concerns monoclonal antibodies which are capable of binding to p100.

Detection and quantification of neu related proteins in the biological fluids of humans

A nucleic acid sequencing gel comprising 2 to 10% of a gelling polysaccharide, preferably agarose; a denaturing agent, a non-gelling additive, preferably glycerol, and electrophoretic buffers. This composition is capable of resolving nucleic acid fragments having at least 50 bases and which differ from each other by at least one base.

Agarose compositions for nucleic acid sequencing

Polysaccharide resolving gels and gel systems for stacking

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Camden, ME, United States of America

Jonathan H Morgan