Eli Lilly and Company

Jonathan Edward Green

Donald Paul Matthews

Prabhakar Kondaji Jadhav

Alan M Warshawsky

Winton Dennis Jones, Jr

Lynn Stacy Gossett

Daryl Lynn Smith

Konstantinos Gavardinas

Michael Joseph Coghlan

Kevin Robert Fales

Jennifer Ann Vance

Leonard Larry Winneroski, Jr

James Joseph Droste

Mitchell I Steinberg

James Robert Henry

Guoxin Zhu

Yanping Xu

Timothy A Grese

Michael Gregory Bell

Nathan Bryan Mantlo

Scott Eugene Conner

Edward C R Smith

David Andrew Neel

Gregory Alan Stephenson

Quanrong Shen

Daniel Ray Mayhugh

Venkatesh Krishnan

Xiaodong Wang

Ashraf Saeed

The present invention provides novel selective androgen receptor modulators and their salts and pharmaceutical compositions thereof. 

4-aminobenzonitrile selective androgen receptor modulators

The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly reduced bones mass, osteoporosis, osteopenia, or reduced muscle mass or strength, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof. X-17142. 

Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators

The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of formula (I). 

Tetrahydrocarbazole derivatives useful as androgen receptor modulators

The present invention provides a compound of the formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof an effective amount of a compound of Formula (I). 

Tricyclic steroid hormone nuclear receptor modulators

The present invention is directed to a compound of Formula (I): and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases. 

Sulfonamide derivatives as PPAR modulators

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof an effective amount of a compound of Formula (I). 

The present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation comprising administering to a patient in need thereof an effective amount of a compound of the formula: or a pharmaceutically acceptable salt thereof. In addition, the present invention provides novel pharmaceutical compounds of Formula I, including the pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions which comprise as an active ingredient a compound of Formula I.

The present invention is directed to a compound of formula I, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomer thereof, which are useful in treating Syndrome X, Type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to Syndrome X as well as cardiovascular diseases.

Modulators of peroxisome proliferator activated receptors (PPAR)

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Avon, IN, United States of America

Jonathan Edward Green