Oxford University Innovation Limited

Jonathan Daly

Lionel Tarassenko

Haemodynamic parameters such as the amplitude and phase of a pulse wave passing through a region of interest can be obtained from a video image of the exposed skin of a patient by processing of the reflectance photoplethysmographic signal using signal averaging. The region of interest is defined and a reflectance photoplethysmographic signal obtained by finding the mean pixel intensity across the region of interest for each video frame. Signal averaging is performed on the resulting pulsatile waveform by detecting peaks in the waveform, selecting those parts of the waveform which lie within a window centered on the peaks, and summing the selected parts of the waveform to find an average pulse waveform. The region of interest is then divided into sub-regions and an average pulse waveform for the video sequence is found for each of the sub-regions in the same way. The amplitudes of the average pulse waveforms for the sub-regions can be measured and displayed, for example as a spatial map across the region of interest. The phase of the average pulse waveforms in the sub-regions in the sub-regions relative to the average pulse waveform for the whole region of interest can be measured and displayed, again as a spatial map. The phase and amplitude maps give an indication of the quality of perfusion across the region of interest.

Growing community of inventors

Oxford, United Kingdom

Jonathan Daly