Abbott Diabetes Care Inc.

Jonathan D Mccanless

Benjamin J Feldman

Tuan Anh Nguyen

Udo Hoss

Steven T Mitchell

Tianmei Ouyang

Louis G Pace

Peter G Robinson

Matthew Simmons

Christopher Allen Thomas

Vivek S Rao

Suyue Qian

Stephen Oja

John V LaTour

Kevin Paul Wallis

Michael E Carroll

Jörn Meissner

Peter M Voit

Christopher M Harris

Johnathan D Manion

Dharmendra Patel

Byron J Lambert

Stephen T Pudjijanto

Hsuehchieh Wu

Carter W Phillip

Vu H Le

Vincent M Dipalma

A sensor control device and methods of making them are described. The sensor control device includes an electronics housing and a plug assembly. The electronics housing includes an upper shell matable to a lower mount having a skin-facing surface. The plug assembly is coupled to the electronics housing and includes a sensor module that has a sensor and a sharp module having a sharp. The plug assembly includes a base having a skin-facing surface and a plug portion comprising a lumen therethrough. At least a portion of a surface of the electronics housing or the plug assembly comprises an antimicrobial agent. The antimicrobial agent may be a metal and/or a metal oxide.

Antimicrobial and microstatic sensor systems

Methods and analyte sensors including a sensor tail comprising at least a first working electrode and a second working electrode that are spaced apart from one another along a length of the sensor tail. A first active area is disposed upon a surface of the first working electrode and a second active area is disposed upon a surface of the second working electrode, the first active area and the second active area being responsive to different analytes. A mass transport limiting membrane is deposited upon the first active area and the second active area by sequential dip coating operations, and the mass transport limiting membrane comprises a bilayer membrane portion overcoating the first active area and a homogeneous membrane portion overcoating the second active area.

Analyte sensors and sensing methods featuring low-potential detection

Analyte sensors responsive at low working electrode potentials may comprise an active area upon a surface of a working electrode, wherein the active area comprises a polymer, a redox mediator covalently bonded to the polymer, and at least one analyte-responsive enzyme covalently bonded to the polymer. A specific redox mediator responsive at low potential may have a structure of wherein G is a linking group covalently bonding the redox mediator to the polymer. A mass transport limiting membrane permeable to the analyte may overcoat the active area. In some sensor configurations, the mass transport limiting membrane may comprise a membrane polymer crosslinked with a branched crosslinker comprising three or more crosslinkable groups, such as polyethylene glycol tetraglycidyl ether.

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Oakland, CA, United States of America

Jonathan D Mccanless