Mentor Corporation

Mills Biopharmaceuticals LLC

Jonathan D Elliott

John J Berkey

Daniel M Elliott

George M Hoedeman

An automated system for loading low dose radioisotope seeds into a plurality of implant needles is comprised of a loading station into which a replaceable cartridge may be positioned. The cartridge is preloaded with a plurality of radioisotope seeds and a plurality of spacers. The cartridge has at least one aperture and preferably the radioisotope seeds and spacers are loaded around the periphery of a rotatable drum within the cartridge. The loading station has a cartridge receiving structure and an automated motion control system. When the cartridge is positioned in the cartridge receiving structure, the automated motion control system preferably drives a pair of stepper motors within the cartridge, one for rotating the rotatable drum and one for sliding a pushrod to selectively eject radioisotope seeds and spacers from the cartridge into each of a plurality of implant needles positioned so as to receive the radioisotopes seeds and spacers within the implant needle. In one embodiment, the implant needles are positioned tip first into the loading station, and once a predetermined arrangement of radioisotope seeds and spacers are loaded into the implant needle, a plug is positioned in the tip of the implant needle. Preferably, the automated system includes a computer processor having a touch screen user interface that is connected to and directs the operation of the automated motion control system to load the plurality of implant needles in accordance with a predetermined dose plan.

Automated radioisotope seed loader system for implant needles

An automated cartridge for use in an automated system for low dose radioisotope procedures is replaceable in the automated system and has a housing that contains a selectively positionable member having a plurality of radioisotope seeds preloaded in chambers defined in the positionable member. An aperture in the housing allows an elongated member to selectively eject radioisotope seeds from chambers in the positionable member when a given chamber is aligned with the aperture. A mechanism in the cartridge automatically positions the selectively positionable member in alignment with the aperture. Preferably, a feedback mechanism generates a positional feedback signal of a position of the chambers of the positionable member relative to the aperture.

Automated radioisotope seed cartridge

A loading clip for low dose radioisotope seeds has a body having a channel defined therein. The channel has a cavity adapted for receiving a radioisotope seed at a distal end. A slider member slidably positionable within the channel has a spring biased tooth at a distal end. A constant force spring member is slidably positioned within the channel between the slider member and the body. Radioisotope seeds are magazined into the loading clip biased against the constant force spring member by operation of the slider member extending the tooth over the cavity and retracting a radioisotope seed in the cavity into the channel. In one embodiment, radioisotope seeds are magazined into the loading clip that is then used to load an automated seed cartridge. In this embodiment, the loading clip has structure for mating with an aperture in the automated seed cartridge so as to introduce radioisotope seeds into the seed cartridge one at a time. Preferably, the loading clip is provided with a machine readable storage medium accessible via an electrical connector that stores indicia representing at least information about the radioisotope seeds located in the loading clip.

Loading clip for radioisotope seeds

An automated system for loading low dose radioisotope seeds into a plurality of implant needles includes a loading station into which a replaceable cartridge may be positioned. The cartridge is preloaded with a plurality of radioisotope seeds and a plurality of spacers. The cartridge has at least one aperture and preferably the radioisotope seeds and spacers are loaded around the periphery of a rotatable drum within the cartridge. The loading station has a cartridge receiving structure and an automated motion control system. When the cartridge is positioned in the cartridge receiving structure, the automated motion control system preferably drives a pair of stepper motors within the cartridge, one for rotating the rotatable drum and one for sliding a pushrod to selectively eject radioisotope seeds and spacers from the cartridge into each of a plurality of implant needles positioned so as to receive the radioisotopes seeds and spacers within the implant needle. In one embodiment, the implant needles are positioned tip first into the loading station, and once a predetermined arrangement of radioisotope seeds and spacers are loaded into the implant needle, a plug is positioned in the tip of the implant needle. Preferably, the automated system includes a computer processor having a touch screen user interface that is connected to and directs the operation of the automated motion control system to load the plurality of implant needles in accordance with a predetermined dose plan.

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Saint Paul, MN, United States of America

Jonathan D Elliott